TNFAIP3, TNF alpha induced protein 3, 7128

N. diseases: 212; N. variants: 29
Disease: Sjogren's Syndrome ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5029939
rs5029939
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C1527336
Disease:
Sjogren's Syndrome 		G 0.800 GeneticVariation GWASCAT A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. 24097066 2013
dbSNP: rs5029939
rs5029939
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C1527336
Disease:
Sjogren's Syndrome 		G 0.800 GeneticVariation GWASDB A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. 24097066 2013
dbSNP: rs2230926
rs2230926
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C1527336
Disease:
Sjogren's Syndrome 		0.020 GeneticVariation BEFREE Increased prevalence of the rs2230926 mutant variant was detected in both SS-lymphoma and SS-nonlymphoma subgroups compared to HC (8.8% vs. 7.6% vs. 3.6%, <i>p</i> values: 0.04 and 0.03, respectively) in association with higher IgM, LDH serum levels, and PB <i>Bcl-XL</i> transcripts but lower leucocyte and neutrophil counts. 30662920 2018
dbSNP: rs2230926
rs2230926
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C1527336
Disease:
Sjogren's Syndrome 		0.020 GeneticVariation BEFREE Genotyping of the most common coding polymorphism, rs2230926, in the MADGC collection and additional control individuals revealed a significant association with Sjögren's syndrome (OR=3.38, P=0.038), Crohn's disease (OR=2.25, P=0.041), psoriasis (OR=0.037, P=0.036) and RA (OR=1.9, P=0.025). 21326317 2011