TYK2, tyrosine kinase 2, 7297

N. diseases: 172; N. variants: 22
Disease: Rheumatoid Arthritis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs34536443
rs34536443
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.830 GeneticVariation BEFREE Computational Molecular Phenotypic Analysis of PTPN22 (W620R), IL6R (D358A), and TYK2 (P1104A) Gene Mutations of Rheumatoid Arthritis. 30899276 2019
dbSNP: rs34536443
rs34536443
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		G 0.830 GeneticVariation GWASCAT Genetic influences on susceptibility to rheumatoid arthritis in African-Americans. 30423114 2019
dbSNP: rs34536443
rs34536443
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.830 GeneticVariation BEFREE Genetic overlap between PsA and RA was detected for the rs34536443 SNP of the TYK2 gene within a Greek population. 27440135 2017
dbSNP: rs34536443
rs34536443
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.830 GeneticVariation BEFREE Finally, in a phenome-wide association study (PheWAS) assessing >500 phenotypes using electronic medical records (EMR) in >29,000 subjects, we found no convincing evidence for association of P1104A and A928V with complex phenotypes other than autoimmune diseases such as RA, SLE and IBD. 25849893 2015
dbSNP: rs34536443
rs34536443
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		C 0.830 GeneticVariation GWASCAT High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. 24532676 2015
dbSNP: rs34536443
rs34536443
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		G 0.830 GeneticVariation GWASDB Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342 2014
dbSNP: rs34536443
rs34536443
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		G 0.830 GeneticVariation GWASCAT Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342 2014
dbSNP: rs34536443
rs34536443
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.830 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2012
dbSNP: rs34536443
rs34536443
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.830 GeneticVariation GWASCAT High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2012
dbSNP: rs11085725
rs11085725
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.700 GeneticVariation GWASCAT Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases. 30573655 2019
dbSNP: rs35018800
rs35018800
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.010 GeneticVariation BEFREE Finally, in a phenome-wide association study (PheWAS) assessing >500 phenotypes using electronic medical records (EMR) in >29,000 subjects, we found no convincing evidence for association of P1104A and A928V with complex phenotypes other than autoimmune diseases such as RA, SLE and IBD. 25849893 2015