UBE2L3, ubiquitin conjugating enzyme E2 L3, 7332

N. diseases: 56; N. variants: 39
Disease: Lupus Erythematosus, Systemic ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs131654
rs131654
Entrez Id: 7332
Gene Symbol: UBE2L3
UBE2L3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		A 0.800 GeneticVariation GWASDB Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193 2009
dbSNP: rs131654
rs131654
Entrez Id: 7332
Gene Symbol: UBE2L3
UBE2L3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		A 0.800 GeneticVariation GWASCAT Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193 2009
dbSNP: rs131658
rs131658
Entrez Id: 7332
Gene Symbol: UBE2L3
UBE2L3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		G 0.700 GeneticVariation GWASCAT Transancestral mapping and genetic load in systemic lupus erythematosus. 28714469 2017
dbSNP: rs2283790
rs2283790
Entrez Id: 7332
Gene Symbol: UBE2L3
UBE2L3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASCAT A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. 27193031 2017
dbSNP: rs7444
rs7444
Entrez Id: 7332
Gene Symbol: UBE2L3
UBE2L3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		G 0.700 GeneticVariation GWASCAT Transancestral mapping and genetic load in systemic lupus erythematosus. 28714469 2017
dbSNP: rs7444
rs7444
Entrez Id: 7332
Gene Symbol: UBE2L3
UBE2L3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASCAT Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus. 27399966 2016
dbSNP: rs7444
rs7444
Entrez Id: 7332
Gene Symbol: UBE2L3
UBE2L3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		C 0.700 GeneticVariation GWASCAT Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. 26502338 2015
dbSNP: rs5754217
rs5754217
Entrez Id: 7332
Gene Symbol: UBE2L3
UBE2L3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. 18204446 2008
dbSNP: rs140490
rs140490
Entrez Id: 7332
Gene Symbol: UBE2L3
UBE2L3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.010 GeneticVariation BEFREE By using data from a genome-wide association study of systemic lupus erythematosus (SLE), we observed a single risk haplotype spanning UBE2L3, consistently aligned across multiple autoimmune diseases, associated with increased UBE2L3 expression in B cells and monocytes. rs140490 in the UBE2L3 promoter region showed the strongest association. 25640675 2015