Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		0.800 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		G 0.800 GeneticVariation GWASCAT Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. 26414677 2015
dbSNP: rs606231343
rs606231343
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C4225402
Disease:
PREMATURE OVARIAN FAILURE 10 		0.800 GeneticVariation UNIPROT Exome sequencing reveals MCM8 mutation underlies ovarian failure and chromosomal instability. 25437880 2015
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASCAT A genome-wide association study of early menopause and the combined impact of identified variants. 23307926 2013
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASDB A genome-wide association study of early menopause and the combined impact of identified variants. 23307926 2013
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		0.800 GeneticVariation GWASDB Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study. 23424626 2013
dbSNP: rs236114
rs236114
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		0.800 GeneticVariation GWASDB Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study. 23424626 2013
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASCAT Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. 22267201 2012
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASDB Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. 22267201 2012
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASCAT Genome-wide association studies identify loci associated with age at menarche and age at natural menopause. 19448621 2009
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASDB Genome-wide association studies identify loci associated with age at menarche and age at natural menopause. 19448621 2009
dbSNP: rs236114
rs236114
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASCAT Loci at chromosomes 13, 19 and 20 influence age at natural menopause. 19448619 2009
dbSNP: rs236114
rs236114
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		A 0.800 GeneticVariation GWASDB Loci at chromosomes 13, 19 and 20 influence age at natural menopause. 19448619 2009
dbSNP: rs606231343
rs606231343
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C4225402
Disease:
PREMATURE OVARIAN FAILURE 10 		G 0.800 CausalMutation CLINVAR
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C2242776
Disease:
Plexiform leiomyoma 		A 0.700 GeneticVariation GWASCAT Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis. 31649266 2019
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C0042133
Disease:
Uterine Fibroids 		A 0.700 GeneticVariation GWASCAT Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis. 31649266 2019
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C0025323
Disease:
Menorrhagia 		A 0.700 GeneticVariation GWASCAT Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis. 31649266 2019
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C4048548
Disease:
Anti-Mullerian Hormone Measurement 		A 0.700 GeneticVariation GWASCAT Genome-wide association study of anti-Müllerian hormone levels in pre-menopausal women of late reproductive age and relationship with genetic determinants of reproductive lifespan. 30649302 2019
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C2242776
Disease:
Plexiform leiomyoma 		A 0.700 GeneticVariation GWASCAT Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits. 30194396 2018
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C0042133
Disease:
Uterine Fibroids 		A 0.700 GeneticVariation GWASCAT Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits. 30194396 2018
dbSNP: rs76498344
rs76498344
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		C 0.700 GeneticVariation GWASCAT Elucidating the genetic architecture of reproductive ageing in the Japanese population. 29773799 2018
dbSNP: rs16991615
rs16991615
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C0678222
Disease:
Breast Carcinoma 		A 0.700 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
dbSNP: rs451417
rs451417
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1629609
Disease:
Age at menopause 		A 0.700 GeneticVariation GWASCAT Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. 26414677 2015
dbSNP: rs454422
rs454422
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1836231
Disease:
HIV-1, RESISTANCE TO 		0.700 GeneticVariation GWASCAT Host determinants of HIV-1 control in African Americans. 20205591 2010
dbSNP: rs454422
rs454422
Entrez Id: 84515
Gene Symbol: MCM8
MCM8
CUI: C1836230
Disease:
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO 		0.700 GeneticVariation GWASCAT Host determinants of HIV-1 control in African Americans. 20205591 2010