IL1RL1, interleukin 1 receptor like 1, 9173
N. diseases: 117; N. variants: 51
Source: ALL
Variant | Gene | Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||||
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0.700 | GeneticVariation | GWASCAT | A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. | 29785011 | 2018 | |||||||
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0.710 | GeneticVariation | GWASDB | A large-scale, consortium-based genomewide association study of asthma. | 20860503 | 2010 | |||||||
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0.700 | GeneticVariation | GWASDB | A large-scale, consortium-based genomewide association study of asthma. | 20860503 | 2010 | |||||||
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0.700 | GeneticVariation | GWASDB | A large-scale, consortium-based genomewide association study of asthma. | 20860503 | 2010 | |||||||
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0.700 | GeneticVariation | GWASDB | A large-scale, consortium-based genomewide association study of asthma. | 20860503 | 2010 | |||||||
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0.820 | GeneticVariation | BEFREE | Association of IL1RL1 rs3771180 and TSLP rs1837253 variants with asthma in the Guangxi Zhuang population in China. | 31066119 | 2019 | |||||||
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0.710 | GeneticVariation | BEFREE | Finally, we determined the association of IL1RL1-a levels with asthma and its clinical characteristics (n=1101).<i>IL1RL1</i> asthma-risk SNPs strongly associated with <i>IL1RL1</i> methylation (rs1420101; p=3.7×10<sup>-16</sup>) and serum IL1RL1-a levels (p=2.8×10<sup>-56</sup>). | 29519908 | 2018 | |||||||
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A | 0.700 | GeneticVariation | GWASCAT | Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. | 30929738 | 2019 | ||||||
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C | 0.700 | GeneticVariation | GWASCAT | Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. | 30929738 | 2019 | ||||||
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T | 0.700 | GeneticVariation | GWASCAT | Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. | 30929738 | 2019 | ||||||
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A | 0.810 | GeneticVariation | GWASCAT | Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. | 24388013 | 2014 | ||||||
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0.010 | GeneticVariation | BEFREE | GSDMB SNP rs2305480 (Ser311Pro) was associated with asthma diagnosis (p = 8.9×10-4), BHR (p = 8.2×10-4) and severity (p = 1.5×10-4) with supporting evidence from a second GSDMB SNP rs11078927 (intronic). | 24066901 | 2013 | |||||||
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0.810 | GeneticVariation | BEFREE | However, a variant in IL1RL1 that is in low linkage disequilibrium with that reported previously was associated with asthma risk after accounting for all variants tested (rs10197862, gene wide P = 0.01). | 21150878 | 2011 | |||||||
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0.710 | GeneticVariation | BEFREE | However, the rs10192157 and rs2899642 mutations were documented with asthma disease. | 31213409 | 2020 | |||||||
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G | 0.700 | GeneticVariation | GWASCAT | Identification of a new locus at 16q12 associated with time to asthma onset. | 27130862 | 2016 | ||||||
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0.010 | GeneticVariation | BEFREE | In the total cohort, rs1041973 allele A was associated with a decreased risk of developing asthma (odds ratio, 0.70; 95% CI, 0.54-0.90). | 21281963 | 2011 | |||||||
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T | 0.710 | GeneticVariation | GWASCAT | Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults. | 30578877 | 2019 | ||||||
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0.820 | GeneticVariation | GWASDB | Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. | 21804549 | 2011 | |||||||
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0.820 | GeneticVariation | GWASCAT | Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. | 21804549 | 2011 | |||||||
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0.810 | GeneticVariation | GWASDB | Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. | 21804549 | 2011 | |||||||
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0.810 | GeneticVariation | GWASDB | Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. | 21804549 | 2011 | |||||||
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0.700 | GeneticVariation | GWASDB | Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. | 21804549 | 2011 | |||||||
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0.700 | GeneticVariation | GWASDB | Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. | 21804549 | 2011 | |||||||
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0.700 | GeneticVariation | GWASDB | Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. | 21804549 | 2011 | |||||||
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T | 0.700 | GeneticVariation | GWASCAT | Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. | 30552067 | 2019 |