NRXN3, neurexin 3, 9369

N. diseases: 64; N. variants: 29
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1004212
rs1004212
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0549393
Disease:
Alcohol problem 		0.010 GeneticVariation BEFREE In men, there were modest associations between rs11624704 and attentional impulsivity (p=0.005) and between rs1004212 and alcohol problems (p=0.009). 21676558 2011
dbSNP: rs11624704
rs11624704
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0549393
Disease:
Alcohol problem 		0.010 GeneticVariation BEFREE In men, there were modest associations between rs11624704 and attentional impulsivity (p=0.005) and between rs1004212 and alcohol problems (p=0.009). 21676558 2011
dbSNP: rs17754467
rs17754467
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.700 GeneticVariation GWASDB Dosage transmission disequilibrium test (dTDT) for linkage and association detection. 23691058 2013
dbSNP: rs8019381
rs8019381
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0002395
Disease:
Alzheimer's Disease 		0.010 GeneticVariation BEFREE We found that the SNP rs8019381 of NRXN3 that is located adjacent to splicing site #5 (SS#5) interacts with the APOE ε4 haplotype and alters NRXN3 transmembrane or soluble isoform expression in AD postmortem cortex. 30902061 2019
dbSNP: rs2217887
rs2217887
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0853193
Disease:
Bipolar I disorder 		0.010 GeneticVariation BEFREE For markers genotyped in replication samples, rs7619173 exhibited a significant association (P(combined) = 2 ∗ 10(-4)) after multiple testing correction, while markers rs11001178 (MYST4) and rs2217887 (NRXN3) showed weak associations (P(combined) = 0.02) with BPD-I. 24444492 2014
dbSNP: rs2370901
rs2370901
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C2985280
Disease:
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		C 0.700 GeneticVariation GWASCAT Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630 2010
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs17109256
rs17109256
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs2370982
rs2370982
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. 26426971 2015
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Genetic studies of body mass index yield new insights for obesity biology. 25673413 2015
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500 2017
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. 28443625 2017
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies 112 new loci for body mass index in the Japanese population. 28892062 2017
dbSNP: rs7144011
rs7144011
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs7144011
rs7144011
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		G 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127 2018
dbSNP: rs72690737
rs72690737
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs8009329
rs8009329
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0005893
Disease:
Body mass index procedure 		0.700 GeneticVariation GWASDB Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. 23001569 2013
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0005893
Disease:
Body mass index procedure 		C 0.700 GeneticVariation GWASDB Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630 2010
dbSNP: rs17109221
rs17109221
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0005910
Disease:
Body Weight 		T 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs10083466
rs10083466
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0006012
Disease:
Borderline Personality Disorder 		0.010 GeneticVariation BEFREE The strongest association with screening positive for BPD was found for the NRXN3 SNP, rs10083466 (p=.0013). 23245376 2013