NRXN3, neurexin 3, 9369

N. diseases: 64; N. variants: 29
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10146997
rs10146997
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0455829
Disease:
Waist Circumference 		G 0.800 GeneticVariation GWASDB In stage 1, 31,373 individuals of Caucasian descent from eight cohort studies confirmed the role of FTO and MC4R and identified one novel locus associated with WC in the neurexin 3 gene [NRXN3 (rs10146997, p = 6.4x10(-7))]. 19557197 2009
dbSNP: rs10146997
rs10146997
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0455829
Disease:
Waist Circumference 		G 0.800 GeneticVariation GWASCAT In stage 1, 31,373 individuals of Caucasian descent from eight cohort studies confirmed the role of FTO and MC4R and identified one novel locus associated with WC in the neurexin 3 gene [NRXN3 (rs10146997, p = 6.4x10(-7))]. 19557197 2009
dbSNP: rs11624704
rs11624704
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0028754
Disease:
Obesity 		0.800 GeneticVariation GWASDB We next examined obesity-related quantitative traits (such as total body weight, waist circumference and waist to hip ratio), and detected genome-wide significant signals between waist to hip ratio and NRXN3 (rs11624704, P = 2.67 × 10(-9)), previously associated with body weight and fat distribution. 21552555 2011
dbSNP: rs11624704
rs11624704
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0028754
Disease:
Obesity 		0.800 GeneticVariation GWASCAT We next examined obesity-related quantitative traits (such as total body weight, waist circumference and waist to hip ratio), and detected genome-wide significant signals between waist to hip ratio and NRXN3 (rs11624704, P = 2.67 × 10(-9)), previously associated with body weight and fat distribution. 21552555 2011
dbSNP: rs2370983
rs2370983
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0028754
Disease:
Obesity 		A 0.800 GeneticVariation GWASDB Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. 23563607 2013
dbSNP: rs2370983
rs2370983
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0028754
Disease:
Obesity 		A 0.800 GeneticVariation GWASCAT Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. 23563607 2013
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0028754
Disease:
Obesity 		T 0.800 GeneticVariation GWASCAT Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. 23563607 2013
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0028754
Disease:
Obesity 		T 0.800 GeneticVariation GWASDB Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. 23563607 2013
dbSNP: rs7144011
rs7144011
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0455829
Disease:
Waist Circumference 		T 0.800 GeneticVariation GWASCAT New genetic loci link adipose and insulin biology to body fat distribution. 25673412 2015
dbSNP: rs7144011
rs7144011
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0455829
Disease:
Waist Circumference 		0.800 GeneticVariation GWASDB NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. 19557197 2009
dbSNP: rs10136360
rs10136360
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0337443
Disease:
Sodium measurement 		G 0.700 GeneticVariation GWASCAT GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits. 31409800 2019
dbSNP: rs10145154
rs10145154
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0455829
Disease:
Waist Circumference 		0.700 GeneticVariation GWASDB NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. 19557197 2009
dbSNP: rs10146997
rs10146997
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		G 0.700 GeneticVariation GWASCAT An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. 28566273 2017
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0578022
Disease:
Finding of body mass index 		C 0.700 GeneticVariation GWASDB Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630 2010
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0578022
Disease:
Finding of body mass index 		0.700 GeneticVariation GWASDB Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. 23001569 2013
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		C 0.700 GeneticVariation GWASCAT Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630 2010
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0005893
Disease:
Body mass index procedure 		0.700 GeneticVariation GWASDB Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. 23001569 2013
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0455829
Disease:
Waist Circumference 		0.700 GeneticVariation GWASDB NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. 19557197 2009
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0005893
Disease:
Body mass index procedure 		C 0.700 GeneticVariation GWASDB Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630 2010
dbSNP: rs11621908
rs11621908
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0424574
Disease:
Duration of sleep 		T 0.700 GeneticVariation GWASCAT Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. 30804565 2019
dbSNP: rs11621908
rs11621908
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0424574
Disease:
Duration of sleep 		C 0.700 GeneticVariation GWASCAT Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates. 30846698 2019
dbSNP: rs11849937
rs11849937
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0270496
Disease:
Schizoaffective disorder, bipolar type 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
dbSNP: rs1396618
rs1396618
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs17109221
rs17109221
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0005910
Disease:
Body Weight 		T 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017