|
Abnormal behavior
|
|
0.010 |
GeneticVariation
|
BEFREE |
To our knowledge, this is the first time rs1800629 has been investigated in PTSD contributing to a growing body of literature that identifies the GG as a risk genotype for psychiatric disorders in Caucasian cohorts.
|
28160694 |
2017 |
|
Acquired Immunodeficiency Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
The association with A-G-A-C haplotype (beta = 0.718; standard error = 0.182; P = 0.0002) and with other 8.1AH-specific haplotypes including the high-producing tumor necrosis factor-alpha haplotype rs909253(G)-rs1800629(A) (beta = 0.308; standard error = 0.140; P = 0.032) were observed only with NHL identified as an AIDS-defining condition, but not as a post-AIDS condition, nor in combined AIDS and post-AIDS cases.
|
31026237 |
2019 |
|
Acute cerebral ischemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The final multivariate model for acute cerebral ischemia risk included high white blood cell count and reticulocyte count, acute chest syndrome rate, and the single nucleotide polymorphisms (SNPs) TEK rs489347 and TNF-α rs1800629.
|
27520094 |
2016 |
|
Acute Chest Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the present study we investigated whether variants at -1082G→A (rs1800896) and -592C→A (rs1800872) of interleukin-10 (IL-10), -1188A→C (rs3212227) of IL-12 p40, -308G→A of tumor necrosis factor-α (TNF-α) (rs1800629), -174G→C of IL-6 (rs1800795) and +874A→T of interferon-γ (IFN-γ) genes (rs2430561) are associated with ACS.
|
22372709 |
2012 |
|
Acute pancreatitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Epistasis analysis revealed that AP susceptibility was increased by interaction between <i>IL23R</i> rs11209026 and <i>TNF</i> rs1800629 (p = 1.205 × 10<sup>-5</sup>; OR<sub>interaction</sub> = 4.031).
|
31044631 |
2019 |
|
Acute periodontitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Tumor necrosis factor-α G-308A (rs1800629) polymorphism and aggressive periodontitis susceptibility: a meta-analysis of 16 case-control studies.
|
26750615 |
2016 |
|
Acute periodontitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
A meta-analysis was performed to assess the effect of TNF-α -308G/A (rs1800629), -238G/A (rs361525) and -863C/A (rs1800630) polymorphisms on either chronic (CP) or aggressive periodontitis (AgP) risk.
|
24905365 |
2014 |
|
Adenocarcinoma Of Esophagus
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results suggest that TNF-α-308 G>A (rs1800629) is not significantly associated with a risk of esophageal squamous cell carcinoma and esophageal adenocarcinoma.
|
27821804 |
2016 |
|
Age related macular degeneration
|
|
0.010 |
GeneticVariation
|
BEFREE |
To study polymorphisms in promotor regions of <i>tumor necrosis factor (TNF)-α TNF-863A/C</i> (rs1800630), <i>TNF-308A/G</i> (rs1800629), and <i>TNF-238A/G</i> (rs361525) in patients with age-related macular degeneration (AMD) and associations of complex <i>TNF-α</i> genotypes with AMD.
|
30662836 |
2019 |
|
Aggressive Periodontitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
A meta-analysis was performed to assess the effect of TNF-α -308G/A (rs1800629), -238G/A (rs361525) and -863C/A (rs1800630) polymorphisms on either chronic (CP) or aggressive periodontitis (AgP) risk.
|
24905365 |
2014 |
|
Aggressive Periodontitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Tumor necrosis factor-α G-308A (rs1800629) polymorphism and aggressive periodontitis susceptibility: a meta-analysis of 16 case-control studies.
|
26750615 |
2016 |
|
Allergic rhinitis (disorder)
|
|
0.020 |
GeneticVariation
|
BEFREE |
Children carrying a minor rs1800629 (TNF) or rs1927911 (TLR4) allele may be at a higher risk of allergic rhinitis.
|
23639307 |
2013 |
|
Allergic rhinitis (disorder)
|
|
0.020 |
GeneticVariation
|
BEFREE |
In TNFA, a significant relationship was also detected between rs1800629 and rs361525 and allergic rhinitis.
|
24654309 |
2013 |
|
Alzheimer's Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
A significant genotype and allele association with AD was observed with rs1800629 in the tumor necrosis factor α (TNF).
|
20693638 |
2010 |
|
Alzheimer's Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
Haplotyping analysis revealed a significant overrepresentation of an rs1799724-T/rs1800629-G haplotype in AD (P=0.012; OR, 1.60; 95% CI, 1.11-2.29), although to a lesser degree than rs1799724-T alone.
|
15895461 |
2005 |
|
Ankylosing spondylitis
|
|
0.030 |
GeneticVariation
|
BEFREE |
For rs1800629, the A allele was also linked to reduced risk of AS (p < 0.0001, OR = 0.54, 95% CI = 0.39-0.74).
|
29230494 |
2018 |
|
Ankylosing spondylitis
|
|
0.030 |
GeneticVariation
|
BEFREE |
While <i>TNF</i>-308 (rs1800629) AA/GA, <i>IL17A</i> (rs2275913) AA/GA, and <i>IL17F</i> (rs763780) CC/TC genotype frequencies were associated, in the dominance inheritance model, with SpA and AS, regardless of gender, the presence of <i>HLA-B27</i>, <i>TNF</i>-238 (rs361525) GA/AA, <i>IL17A</i> (rs2275913) AA/GA, and <i>IL17F</i> (rs763780) genotypes was associated with PsA.
|
29849482 |
2018 |
|
Ankylosing spondylitis
|
|
0.030 |
GeneticVariation
|
BEFREE |
We replicated associations between AS and the polymorphisms in TNF (rs1800629), TNFRSF1A (rs4149570), and IL23R (rs11209026).
|
30208882 |
2018 |
|
Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
To assess the influence of the TNFA rs1800629 (G > A) polymorphism in the risk of cardiovascular (CV) disease and subclinical atherosclerosis in patients with rheumatoid arthritis (RA).
|
21420089 |
2011 |
|
Arthritis, Psoriatic
|
|
0.020 |
GeneticVariation
|
BEFREE |
While <i>TNF</i>-308 (rs1800629) AA/GA, <i>IL17A</i> (rs2275913) AA/GA, and <i>IL17F</i> (rs763780) CC/TC genotype frequencies were associated, in the dominance inheritance model, with SpA and AS, regardless of gender, the presence of <i>HLA-B27</i>, <i>TNF</i>-238 (rs361525) GA/AA, <i>IL17A</i> (rs2275913) AA/GA, and <i>IL17F</i> (rs763780) genotypes was associated with PsA.
|
29849482 |
2018 |
|
Arthritis, Psoriatic
|
|
0.020 |
GeneticVariation
|
BEFREE |
The association to PsA was observed in the presence of polymorphisms: TNF-238 G > A (rs361525), -308 G > A (rs1800629), and -857 C > T (rs1799724); IL12B C > G (rs6887695) and A > C (rs3212227); IL23A A > G (rs2066808) and IL23R G > A (rs11209026).
|
30584776 |
2019 |
|
Aspirin exacerbated respiratory disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The GA genotype of rs1800629 is associated with genetic susceptibility to AERD, but it does not correlate to protein serum levels.
|
29172674 |
2017 |
|
Asthma
|
|
0.030 |
GeneticVariation
|
BEFREE |
GSTP1 rs1138272 and TNF rs1800629 SNPs were associated with asthma and wheeze, respectively.
|
24465030 |
2014 |
|
Asthma
|
|
0.030 |
GeneticVariation
|
BEFREE |
This meta-analysis suggested that the rs1800629 polymorphism in TNF-α was a risk factor for asthma.
|
24936650 |
2014 |
|
Asthma
|
|
0.030 |
GeneticVariation
|
BEFREE |
To investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.
|
22376040 |
2012 |