|
Mental Depression
|
|
0.010 |
GeneticVariation
|
BEFREE |
Considering the inflammatory-depression link, and that women are twice as likely to experience depression compared to men, the current study (<i>N</i> = 475 university students) examined the moderating role of three independent cytokine single nucleotide polymorphisms (SNPs; IL-1β rs16944, IL-6 rs1800795 SNP, TNF-α rs1800629) in the relationship between early-life adversity and depressive symptoms, and whether these relations differed between males and females.
|
30967802 |
2019 |
|
Respiratory Distress Syndrome, Adult
|
|
0.010 |
GeneticVariation
|
BEFREE |
The TNF-α rs1800629 locus A allele and the IL-6 rs1800796 locus G allele were found to be risk factors for ARDS (adjusted OR = 1.452, 95% CI: 1.211-1.689, P < .001 and adjusted OR = 1.205, 95% CI: 1.058-1.358, P = .005, respectively).
|
31261506 |
2019 |
|
Glaucoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Thus present study aimed to analyze the association of TNF-α promoter region alterations (c.-238G>A (rs361525), c.-308G>A (rs1800629), c.-857C>T (rs1799724) and c.-863C>A (rs1800630)) with glaucoma in north Indian cohort.
|
31132515 |
2019 |
|
Depressed mood
|
|
0.010 |
GeneticVariation
|
BEFREE |
Considering the inflammatory-depression link, and that women are twice as likely to experience depression compared to men, the current study (<i>N</i> = 475 university students) examined the moderating role of three independent cytokine single nucleotide polymorphisms (SNPs; IL-1β rs16944, IL-6 rs1800795 SNP, TNF-α rs1800629) in the relationship between early-life adversity and depressive symptoms, and whether these relations differed between males and females.
|
30967802 |
2019 |
|
Cirrhosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
TNF-α rs1800629 polymorphism is a potential genetic-susceptibility factor for HCV related cirrhosis and HCC progression.
|
30204505 |
2019 |
|
Age related macular degeneration
|
|
0.010 |
GeneticVariation
|
BEFREE |
To study polymorphisms in promotor regions of <i>tumor necrosis factor (TNF)-α TNF-863A/C</i> (rs1800630), <i>TNF-308A/G</i> (rs1800629), and <i>TNF-238A/G</i> (rs361525) in patients with age-related macular degeneration (AMD) and associations of complex <i>TNF-α</i> genotypes with AMD.
|
30662836 |
2019 |
|
Acquired Immunodeficiency Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
The association with A-G-A-C haplotype (beta = 0.718; standard error = 0.182; P = 0.0002) and with other 8.1AH-specific haplotypes including the high-producing tumor necrosis factor-alpha haplotype rs909253(G)-rs1800629(A) (beta = 0.308; standard error = 0.140; P = 0.032) were observed only with NHL identified as an AIDS-defining condition, but not as a post-AIDS condition, nor in combined AIDS and post-AIDS cases.
|
31026237 |
2019 |
|
Leukemia, Myelocytic, Acute
|
|
0.010 |
GeneticVariation
|
BEFREE |
We aimed to evaluate the multivariate effect of TNF-α rs361525, rs1800750, rs1800629, IL-10 rs1800896, rs1800872, IL-6 rs1800795, TGF-β1 rs1800470, IFN-γ rs2430561 single nucleotide polymorphisms (SNPs) on AML risk, the multivariate effect of SNPs on overall survival (OS) in AML and the association between the investigated SNPs and prognostic factors in AML.
|
31373163 |
2019 |
|
Acute pancreatitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Epistasis analysis revealed that AP susceptibility was increased by interaction between <i>IL23R</i> rs11209026 and <i>TNF</i> rs1800629 (p = 1.205 × 10<sup>-5</sup>; OR<sub>interaction</sub> = 4.031).
|
31044631 |
2019 |
|
Liver Cirrhosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
TNF-α rs1800629 polymorphism is a potential genetic-susceptibility factor for HCV related cirrhosis and HCC progression.
|
30204505 |
2019 |
|
Irritable Bowel Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
No evidence supported the association of GNβ3 rs5443, TNFα rs1800629, and IL10 rs1800871 to IBS in this study.
|
31615448 |
2019 |
|
Japanese Encephalitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
TNFA rs1800629 A and CCR5 rs1799987 A alleles were associated with susceptibility while combination lacking TNFA rs1800629 A, CCR5 rs333 Δ32, and rs1799987 A alleles and CCL2 rs1024611 G/G genotype was associated with protection to JE.
|
31479868 |
2019 |
|
Depressive disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
Considering the inflammatory-depression link, and that women are twice as likely to experience depression compared to men, the current study (<i>N</i> = 475 university students) examined the moderating role of three independent cytokine single nucleotide polymorphisms (SNPs; IL-1β rs16944, IL-6 rs1800795 SNP, TNF-α rs1800629) in the relationship between early-life adversity and depressive symptoms, and whether these relations differed between males and females.
|
30967802 |
2019 |
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Promoter variants of TNF-α rs1800629 and IL-10 rs1800871 are independently associated with the susceptibility of coronary artery disease in north Indian.
|
29734056 |
2018 |
|
Febrile Convulsions
|
|
0.010 |
GeneticVariation
|
BEFREE |
Expression of these cytokines can be modulated by polymorphisms such as rs16944 and rs1800629, respectively, both of which have been associated with febrile seizures (FS) and MTLE-HS development.
|
28675059 |
2018 |
|
Cardiomyopathy, Dilated
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association between rs1800629 polymorphism in tumor necrosis factor-α gene and dilated cardiomyopathy susceptibility: Evidence from case-control studies.
|
30557992 |
2018 |
|
Proliferative vitreoretinopathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, 96 healthy controls were investigated within 4 SNPs: rs17561 (<i>IL1A</i>), rs2069763 (<i>IL2</i>), rs2229094 (<i>LTA</i>), and rs1800629 (<i>TNF</i>) in comparison to PVR patients.
|
29862067 |
2018 |
|
Diabetic foot ulcer
|
|
0.010 |
GeneticVariation
|
BEFREE |
The Interleukin (IL)-6 (-174G > C/rs1800795), Tumor Necrosis Factor (TNF)-α (-308G > A/rs1800629) and (-238G > A/rs361525) and Stromal cell Derived Factor (SDF)-1 (+801G > A/rs1801157) are well characterized single nucleotide polymorphisms (SNPs) which were previously shown to be associated with Diabetic Foot Ulcer (DFU).
|
30009916 |
2018 |
|
Mesial temporal lobe epilepsy with hippocampal sclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
No association was observed between rs1800629 genotypes or HLA-DRB1 alleles and MTLE-HS susceptibility.
|
28675059 |
2018 |
|
Osteoporosis, Postmenopausal
|
|
0.010 |
GeneticVariation
|
BEFREE |
We have shown that a TNFα gene polymorphism, rs1800629, is highly significantly associated with postmenopausal osteoporosis and BMD in the female Han Chinese population.
|
29481288 |
2018 |
|
Neck Pain
|
|
0.010 |
GeneticVariation
|
BEFREE |
TNFα rs1800629 GA genotype may increase the incidence of neck pain compared with GG genotype.
|
30430914 |
2018 |
|
Spondylarthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
While <i>TNF</i>-308 (rs1800629) AA/GA, <i>IL17A</i> (rs2275913) AA/GA, and <i>IL17F</i> (rs763780) CC/TC genotype frequencies were associated, in the dominance inheritance model, with SpA and AS, regardless of gender, the presence of <i>HLA-B27</i>, <i>TNF</i>-238 (rs361525) GA/AA, <i>IL17A</i> (rs2275913) AA/GA, and <i>IL17F</i> (rs763780) genotypes was associated with PsA.
|
29849482 |
2018 |
|
Diabetic Nephropathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
The present study was designed to investigate the association of TNF-α [-308G/A, (rs1800629)] single nucleotide polymorphism (SNP) on the susceptibility to DN subjects and to correlate it with the plasma levels of TNF-α along with circulatory TNF-α receptor super family cytokines (sTNFR-1 and sTNFR-2).
|
29042282 |
2018 |
|
Graves Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Together, our data support that only the promoter single-nucleotide polymorphism (SNP) rs1800629 within the <i>TNF</i>-α gene is associated with increased risk for developing GD, especially in European population.
|
29440561 |
2018 |
|
Cardiomyopathy, Familial Idiopathic
|
|
0.010 |
GeneticVariation
|
BEFREE |
There may be a moderate association between TNF-α rs1800629 polymorphism and DCM susceptibility in the whole populations studied; however, TNF-α rs1800629 polymorphism was significantly associated with the susceptibility of DCM for Asians, which indicates that such associations may be different between ethnicities.
|
30557992 |
2018 |