Malignant Neoplasms
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our study demonstrates that rs1800796 is significantly associated with cancer risk in three genetic models (allele G vs allele C, pooled OR = 1.182, P = 0.009; CG + GG vs CC, pooled OR = 1.333, P = 0.006; CG vs CC, pooled OR = 1.323, P = 0.007).Our meta-analysis suggests that polymorphism rs1800796 within the IL6 gene may be a potential risk factor for cancer.
|
26535637 |
2015 |
Primary malignant neoplasm
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our study demonstrates that rs1800796 is significantly associated with cancer risk in three genetic models (allele G vs allele C, pooled OR = 1.182, P = 0.009; CG + GG vs CC, pooled OR = 1.333, P = 0.006; CG vs CC, pooled OR = 1.323, P = 0.007).Our meta-analysis suggests that polymorphism rs1800796 within the IL6 gene may be a potential risk factor for cancer.
|
26535637 |
2015 |
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The present meta-analysis suggested that there was no association between IL-6 rs1800796 polymorphism and lung cancer, which was independent of smoking status.
|
24984610 |
2014 |
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
CRP rs2794520 (OR=1.64, 95% CI=1.19-2.26) and IL6 rs1800796 (OR=1.41, 95% CI=1.02-1.96) were associated with lung cancer risk.
|
24139238 |
2014 |
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
CRP rs2794520 (OR=1.64, 95% CI=1.19-2.26) and IL6 rs1800796 (OR=1.41, 95% CI=1.02-1.96) were associated with lung cancer risk.
|
24139238 |
2014 |
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The present meta-analysis suggested that there was no association between IL-6 rs1800796 polymorphism and lung cancer, which was independent of smoking status.
|
24984610 |
2014 |
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
CRP rs2794520 (OR=1.64, 95% CI=1.19-2.26) and IL6 rs1800796 (OR=1.41, 95% CI=1.02-1.96) were associated with lung cancer risk.
|
24139238 |
2014 |
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The present meta-analysis suggested that there was no association between IL-6 rs1800796 polymorphism and lung cancer, which was independent of smoking status.
|
24984610 |
2014 |
Primary malignant neoplasm
|
|
0.030 |
GeneticVariation
|
BEFREE |
Having a C allele of the rs1800796 IL6 polymorphisms and the GG genotype of the rs1800795 IL6 polymorphisms was associated with a statistically significantly reduced the risk of colon (OR 0.76 95% CI 0.57, 1.00), but not rectal (OR 1.49 95% CI 1.02,2.16) cancer.
|
17694420 |
2007 |
Malignant Neoplasms
|
|
0.030 |
GeneticVariation
|
BEFREE |
Having a C allele of the rs1800796 IL6 polymorphisms and the GG genotype of the rs1800795 IL6 polymorphisms was associated with a statistically significantly reduced the risk of colon (OR 0.76 95% CI 0.57, 1.00), but not rectal (OR 1.49 95% CI 1.02,2.16) cancer.
|
17694420 |
2007 |
Sleep Apnea, Obstructive
|
|
0.020 |
GeneticVariation
|
BEFREE |
We found VWF rs1063856 (OR = 1.50, 95% CIs = 1.10-2.04; p = 0.010), IL-6 rs1800796 (OR = 1.32, 95% CIs = 1.11-1.56; p = 0.002), TNF rs1800629 (OR = 1.44, 95% CIs = 1.13-1.83; p = 0.003), and CRP rs2794521 (OR = 1.27, 95% CIs = 1.04-1.55; p = 0.021) were all significantly associated with increased susceptibility of OSA, while VWF rs1063856 (OR = 1.75, 95% CIs = 1.18-2.62; p = 0.006), IL-6 rs1800796 (OR = 1.39, 95% CIs = 1.10-1.76; p = 0.006) were associated with the severity of OSA.
|
31210414 |
2019 |
Obesity
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our results suggested that the C allele of rs1800796 and the C allele of rs2069849 of IL-6 gene interaction between rs1800796 and abdominal obesity were all associated with increased OST risk.
|
31301734 |
2019 |
Diabetic Nephropathy
|
|
0.020 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that IL-6 rs1800795, rs1800796 and rs1800797 played important roles in DN development while IL-6 rs2069837 and rs2069840 might not be related to DN.
|
31451183 |
2019 |
Colorectal Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Furthermore, rs1800796 was significantly associated with increased risk of lung cancer, prostate cancer and colorectal cancer but not gastric cancer.
|
29552316 |
2018 |
Tuberculosis
|
|
0.020 |
GeneticVariation
|
BEFREE |
rs1800796 of the IL6 gene is associated with increased risk for anti-tuberculosis drug-induced hepatotoxicity in Chinese Han children.
|
30029918 |
2018 |
Malignant neoplasm of breast
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our results suggest that the contribution of diabetes to breast cancer risk might be modified by IL-6 rs1800796 and HSPD1 rs2605039.
|
28591216 |
2017 |
Breast Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our results suggest that the contribution of diabetes to breast cancer risk might be modified by IL-6 rs1800796 and HSPD1 rs2605039.
|
28591216 |
2017 |
Diabetes Mellitus
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our results suggest that the contribution of diabetes to breast cancer risk might be modified by IL-6 rs1800796 and HSPD1 rs2605039.
|
28591216 |
2017 |
Diabetes
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our results suggest that the contribution of diabetes to breast cancer risk might be modified by IL-6 rs1800796 and HSPD1 rs2605039.
|
28591216 |
2017 |
Congenital Dysplasia Of The Hip
|
|
0.020 |
GeneticVariation
|
BEFREE |
Further research is needed to validate the weak association between rs1800796 in IL-6 and DDH.
|
28860542 |
2017 |
Malignant neoplasm of prostate
|
|
0.020 |
GeneticVariation
|
BEFREE |
Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated to assess the association between rs1800796 and prostate cancer susceptibility.
|
27706719 |
2016 |
Prostate carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated to assess the association between rs1800796 and prostate cancer susceptibility.
|
27706719 |
2016 |
Diabetic Nephropathy
|
|
0.020 |
GeneticVariation
|
BEFREE |
Pro-inflammatory cytokines, such as interleukin-6 (IL-6), have been considered as key factors in type 1 diabetes mellitus (T1DM) and diabetic nephropathy, thus, our aim was to investigate the association of IL6-174G>C (rs1800795) and -634C>G (rs1800796) polymorphisms with T1DM susceptibility and diabetic nephropathy.
|
25384728 |
2015 |
Malignant neoplasm of prostate
|
|
0.020 |
GeneticVariation
|
BEFREE |
In conclusion, we suggest that the IL-6-572C>G (rs1800796) gene polymorphism influences the development of prostate cancer.
|
26535651 |
2015 |
Prostate carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
In conclusion, we suggest that the IL-6-572C>G (rs1800796) gene polymorphism influences the development of prostate cancer.
|
26535651 |
2015 |