|
Myocardial Ischemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
PPARG2 Pro12Ala and TNF<i>α</i> -308G>A Polymorphisms Are Not Associated with Heart Failure Development in Patients with Ischemic Heart Disease after Coronary Artery Bypass Grafting.
|
31275366 |
2019 |
|
Congestive heart failure
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our study did not reveal any correlation between the <i>PPARG2</i> Pro12Ala and <i>TNFα</i> -308G>A polymorphisms and development of HF in patients with ischemic heart disease after coronary bypass grafting.
|
31275366 |
2019 |
|
Heart failure
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our study did not reveal any correlation between the <i>PPARG2</i> Pro12Ala and <i>TNFα</i> -308G>A polymorphisms and development of HF in patients with ischemic heart disease after coronary bypass grafting.
|
31275366 |
2019 |
|
Connective Tissue Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of the research genetic study was to investigate the association between variants (C1431T and Pro12Ala) of the peroxisome proliferator-activated receptor (<i>PPARgamma-2</i>) gene, Trp64Arg polymorphism of the beta-3-adrenergic receptor gene and lipid profile in Polish population including group of 103 patients with connective tissue disease (CTD) and 103 sex-and age-matched controls in context of statin use.
|
29606859 |
2018 |
|
Retinal Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
These findings suggest no significant association of p.Pro12Ala polymorphism with retinopathy in tested type 2 diabetic retinopathy patients as compared to T2DM individuals take as controls.
|
27427939 |
2017 |
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
There was a significant association between PPAR-γ rs1805192 genotypes and decreased SLE risk, and a potential gene-gene interaction between rs1805192 and rs10865710.
|
27324555 |
2016 |
|
Chronic Kidney Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
Compared to ESRD patients, non-CKD subjects were more likely to have T allele at SOD2 Val16Ala (p = 0.036) and CC genotype at PPAR-γ Pro12Ala (p = 0.028).
|
26881045 |
2016 |
|
Cerebral Infarction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Therefore, the Pro12Ala mutation of PPARg2 may not be associated with cerebral infarction in the Inner Mongolian Han Chinese population.
|
27420933 |
2016 |
|
CATARACT, ANTERIOR POLAR
|
|
0.010 |
GeneticVariation
|
BEFREE |
Carotid artery plaque (CAP) and carotid intima-media thickness (CIMT) in HD patients with CT + TT or Pro12Ala genotypes were also less than that in patients with CCor Pro12Pro genotypes, respectively.
|
25096510 |
2014 |
|
Huntington Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results indicate that the Pro12Ala and C161T polymorphisms were associated with some important risk factors for CVD in HD patients in the Han Chinese population.
|
25096510 |
2014 |
|
metabolic disturbance
|
|
0.010 |
GeneticVariation
|
BEFREE |
Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro12Ala) polymorphism has been associated with lower risk of metabolic disturbance and atherosclerosis.
|
25159899 |
2014 |
|
Hodgkin Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results indicate that the Pro12Ala and C161T polymorphisms were associated with some important risk factors for CVD in HD patients in the Han Chinese population.
|
25096510 |
2014 |
|
Human immunodeficiency virus (HIV) II infection category B1
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to analyze the association between the Pro12Ala polymorphism and cardiometabolic risk factors in human immunodeficiency virus (HIV)/Hepatitis C virus (HCV)-coinfected patients.
|
25159899 |
2014 |
|
Hepatitis C
|
|
0.010 |
GeneticVariation
|
BEFREE |
PPARγ2 Pro12Ala polymorphism was associated with favorable cardiometabolic risk profile in HIV/HCV coinfected patients: a cross-sectional study.
|
25159899 |
2014 |
|
Proliferative diabetic retinopathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of Pro12Ala polymorphism in peroxisome proliferator activated receptor gamma with proliferative diabetic retinopathy.
|
23559865 |
2013 |
|
Obesity, Morbid
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, we investigated the association of PPAR-γ gene Pro12Ala (rs1801282) and C1431T (rs3856806) polymorphisms with morbid obesity and related phenotypes, in north Indian population.
|
22410809 |
2012 |
|
Obstructive sleep apnea hypopnea syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this Chinese cohort, the Pro12Ala polymorphism of peroxisome proliferator activated receptor gamma was not associated with obstructive sleep apnoea hypopnoea syndrome, but was associated with increased hyperlipidaemia risk.
|
21669017 |
2011 |
|
Hyperlipidemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this Chinese cohort, the Pro12Ala polymorphism of peroxisome proliferator activated receptor gamma was not associated with obstructive sleep apnoea hypopnoea syndrome, but was associated with increased hyperlipidaemia risk.
|
21669017 |
2011 |
|
Chronic Obstructive Airway Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The minor His447His allele of PPARG significantly increased; and the haplotype containing the minor Pro12Ala and the major His447His polymorphisms of PPARG decreased the risk of COPD.
|
21044285 |
2010 |
|
Fatty Liver, Alcoholic
|
|
0.010 |
GeneticVariation
|
BEFREE |
To test the occurrence of the Pro12Ala mutation of the peroxisome proliferator-activated receptor-γ (PPARγ)2-gene in patients with non-alcoholic fatty liver disease (NAFLD) or alcoholic fatty liver disease (AFLD).
|
21155004 |
2010 |
|
Carcinogenesis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association between peroxisome proliferator-activated receptor-γ gene polymorphism (Pro12Ala) and Helicobacter pylori infection in gastric carcinogenesis.
|
20568969 |
2010 |
|
Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two common variations of PPARgamma, P12A (Pro12Ala, rs1801282) and C161T (His447His, rs3856806), are thought to have an effect on susceptibility to various carcinomas but the results are inconsistent.
|
20596649 |
2010 |
|
Premature adrenarche
|
|
0.010 |
GeneticVariation
|
BEFREE |
Polymorphism Pro12Ala of PPARG in prepubertal children with premature adrenarche and its association with growth in healthy children.
|
20606394 |
2010 |
|
Gastrointestinal Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
One hundred and fifty-five patients with upper gastrointestinal diseases (76 peptic ulcer and 79 non-cardia gastric cancer) and 152 matched controls were genotyped for PPAR-γ gene polymorphism (Pro12Ala) by the PCR-RFLP method.
|
20568969 |
2010 |
|
Graves Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The distribution of the Pro(12)Ala PPAR gamma gene polymorphism is equally present in patients with GD with or without TAO.
|
18624999 |
2009 |