|
Metabolic Syndrome X
|
|
0.010 |
GeneticVariation
|
BEFREE |
Interaction between Vascular Endothelial Growth Factor-A (rs2010963) Gene Polymorphisms and Dietary Diversity Score on Cardiovascular Risk Factors in Patients with Metabolic Syndrome.
|
31786572 |
2020 |
|
Tumor Angiogenesis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Three polymorphisms within the <i>VEGFA</i> (rs699947, rs1570360, and rs2010963) gene were chosen for investigation due to their significance in the angiogenesis signalling pathway and previous associations with risk of ACLRs.
|
30899133 |
2019 |
|
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to evaluate the possible associations between the +405 G/C single nucleotide polymorphisms (SNP) of the VEGF gene (rs2010963) and vitiligo.
|
31135085 |
2019 |
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, VEGF -634G/C gene polymorphism (rs2010963) was not associated with SLE risk.
|
30902069 |
2019 |
|
Vitiligo
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to evaluate the possible associations between the +405 G/C single nucleotide polymorphisms (SNP) of the VEGF gene (rs2010963) and vitiligo.
|
31135085 |
2019 |
|
Gestational Diabetes
|
|
0.010 |
GeneticVariation
|
BEFREE |
The carrier with the rs2146323 AA, CA+AA genotypes, and A allele, as well as the rs3025039 CT, TT, CT+TT genotypes, and T allele showed the increased risk of GDM (all P < 0.05), but the distributions of genotype and allele at rs2010963, rs3025010, and rs833069 were not significantly different between GDM patients and controls (all P > 0.05).
|
30350881 |
2019 |
|
Adult Glioblastoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Also, the VEGF polymorphisms rs3024994, rs2010963, and particularly the homozygous carriers of rs1005230 were associated with a worse prognosis for glioma and glioblastoma.
|
29584591 |
2018 |
|
Childhood Glioblastoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Also, the VEGF polymorphisms rs3024994, rs2010963, and particularly the homozygous carriers of rs1005230 were associated with a worse prognosis for glioma and glioblastoma.
|
29584591 |
2018 |
|
Myocardial Ischemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Moreover, VEGF rs699947 and rs2010963 polymorphisms may serve as genetic biomarkers of poor collateral circulation after myocardial ischemia.
|
30317903 |
2018 |
|
Infantile hemangioma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The purpose of this study was to evaluate the influence of selected polymorphisms in the genes coding for VEGF-A (+405 G/C, rs2010963; +936 C/T, rs3025039) and its receptor VEGFR-2 (+1416 T/A, rs1870377; -271 G/A, rs7667298) on the susceptibility to infantile hemangioma.
|
29984822 |
2018 |
|
Malignant neoplasm of stomach
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the case-control study, rs1042522 (<i>TP53</i>) was associated with a stronger risk for developing gastric cancer in the sample stratified for diffuse subtype patients when compared to the risk observed for the total cases; CTC haplotype (rs699947/rs833061/rs2010963 <i>VEGFA</i>) was associated with risk while rs699947 was associated with protection for gastric malignancy in the total sample.
|
30551681 |
2018 |
|
Strawberry nevus of skin
|
|
0.010 |
GeneticVariation
|
BEFREE |
The purpose of this study was to evaluate the influence of selected polymorphisms in the genes coding for VEGF-A (+405 G/C, rs2010963; +936 C/T, rs3025039) and its receptor VEGFR-2 (+1416 T/A, rs1870377; -271 G/A, rs7667298) on the susceptibility to infantile hemangioma.
|
29984822 |
2018 |
|
Varicosity
|
|
0.010 |
GeneticVariation
|
BEFREE |
Results Allele rs2010963 C was associated with the decreased risk of varicose veins (additive model of inheritance: odds ratio = 0.73, 95% confidence interval = 0.59-0.91, P = 0.004).
|
27932624 |
2018 |
|
Cardiovascular Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
Rigorous analysis evidenced the association of <i>VEGFA</i> rs2010963 and <i>SIRT1</i> rs7896005 with HDL-C and DBP respectively; these traits are known predictors of cardiovascular complications, which increase the risk of cardiovascular diseases in this population.
|
30393491 |
2018 |
|
Anthracosilicosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Associations of polymorphisms in the cytokine genes IL1β (rs16944), IL6 (rs1800795), IL12b (rs3212227) and growth factor VEGFA (rs2010963) with anthracosilicosis in coal miners in Russia and related genotoxic effects.
|
29378067 |
2018 |
|
Carcinoma of bladder
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that the A allele of rs699947 and the A allele of rs833052 within VEGF gene, interaction between rs2010963 and smoking, haplotype containing the rs2010963- C and rs833052- A alleles were all associated with increased bladder cancer risk.
|
28206971 |
2017 |
|
Malignant neoplasm of urinary bladder
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that the A allele of rs699947 and the A allele of rs833052 within VEGF gene, interaction between rs2010963 and smoking, haplotype containing the rs2010963- C and rs833052- A alleles were all associated with increased bladder cancer risk.
|
28206971 |
2017 |
|
Metastatic Renal Cell Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, <i>VEGFA</i> rs2010963 was associated with poorer PFS of mRCC (<i>n</i> = 1).
|
28978162 |
2017 |
|
Proliferative retinopathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
To assess if the included vascular endothelial growth factor (VEGF) polymorphisms rs3025035, rs3025021 and rs2010963 are associated to proliferative retinopathy in a Mexican population with type 2 diabetes mellitus (T2DM).
|
28149790 |
2017 |
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
These results indicate that interactions between the VEGF rs2010963 polymorphism and environment increases the risk of developing MDD.
|
28448948 |
2017 |
|
Bladder Neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that the A allele of rs699947 and the A allele of rs833052 within VEGF gene, interaction between rs2010963 and smoking, haplotype containing the rs2010963- C and rs833052- A alleles were all associated with increased bladder cancer risk.
|
28206971 |
2017 |
|
Metastatic Renal Cell Cancer
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, <i>VEGFA</i> rs2010963 was associated with poorer PFS of mRCC (<i>n</i> = 1).
|
28978162 |
2017 |
|
Palmar-plantar erythrodysesthesia syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that the VEGF rs2010963 CG + GG genotypes had a significantly increased risk of hand-foot syndrome, and the ABCB1 rs1045642 CT + TT genotypes had an increased risk of high blood pressure.
|
26830973 |
2016 |
|
Carotid Atherosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Vascular Endothelial Growth Factor Gene Polymorphism (rs2010963) and Its Receptor, Kinase Insert Domain-Containing Receptor Gene Polymorphism (rs2071559), and Markers of Carotid Atherosclerosis in Patients with Type 2 Diabetes Mellitus.
|
26881237 |
2016 |
|
Ankylosing spondylitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Significant differences were found between the VEGF rs2010963 G/C genotypes and elevated plasma level in AS patients when compared with the controls.
|
27637764 |
2016 |