|
Secondary malignant neoplasm of lymph node
|
|
0.010 |
GeneticVariation
|
BEFREE |
In multivariate analysis, lymph node metastasis was associated with cancer recurrence, and lymph node metastasis and FGFR4 rs351855 were associated with patient survival.
|
28378614 |
2018 |
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Gender-Specific Association Between FGFR4 Gly388Arg Gene Variants and Hypertension.
|
28650667 |
2017 |
|
Malignant tumor of cervix
|
|
0.010 |
GeneticVariation
|
BEFREE |
To discuss the association between FGFR4 gene polymorphism rs351855 (Glu388Aly) and the susceptibility and chemotherapeutic effect of cervical cancer infected by high-risk type HPV.
|
28870344 |
2017 |
|
Cardiovascular Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
The FGFR4 Gly388Arg polymorphism is associated with cancer and cardiovascular diseases, but its association with hypertension is unclear.
|
28650667 |
2017 |
|
Cervix carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
To discuss the association between FGFR4 gene polymorphism rs351855 (Glu388Aly) and the susceptibility and chemotherapeutic effect of cervical cancer infected by high-risk type HPV.
|
28870344 |
2017 |
|
cervical cancer
|
|
0.010 |
GeneticVariation
|
BEFREE |
To discuss the association between FGFR4 gene polymorphism rs351855 (Glu388Aly) and the susceptibility and chemotherapeutic effect of cervical cancer infected by high-risk type HPV.
|
28870344 |
2017 |
|
Neuroendocrine Tumors
|
|
0.010 |
GeneticVariation
|
BEFREE |
The Gly388Arg FGFR4 polymorphism does not seem to have a prognostic value in digestive NET.
|
26335532 |
2016 |
|
Squamous cell carcinoma of oropharynx
|
|
0.010 |
GeneticVariation
|
BEFREE |
The FGFR4 gene was amplified in 0.47% (1/212) of OSCCs and 0.42% (1/238) of OPSCCs, and the FGFR4 Gly388Arg polymorphism was detected in 62% (47/76) of OPSCCs.
|
26551585 |
2015 |
|
Liver Cirrhosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our findings suggest that genetic polymorphism in FGFR4 rs351855 may be associated with the risk of HCC coupled with liver cirrhosis and may markedly increase the AFP level in Taiwanese patients with HCC.
|
25860955 |
2015 |
|
Lymphoma, Non-Hodgkin
|
|
0.010 |
GeneticVariation
|
BEFREE |
These results suggest that FGFR4 rs351855G/A polymorphism is associated with increased susceptibility to NHL and could be used as a marker for predicting the prognosis of the malignancy.
|
24248544 |
2014 |
|
Febrile Neutropenia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Other significant factors for FN in any cycle were higher alanine aminotransferase (OR = 1.02 [1.01; 1.03]), carriers of the rs246221 variant C-allele (OR = 2.0 [1.03; 3.86]) in MRP1 and the rs351855 variant C-allele (OR = 2.48 [1.13; 5.44]) in FGFR4.
|
24641830 |
2014 |
|
Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.
|
23747250 |
2013 |
|
Diabetes
|
|
0.010 |
GeneticVariation
|
BEFREE |
The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.
|
23747250 |
2013 |
|
Non-Small Cell Lung Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs351855G/A polymorphisms of FGFR4 gene can be used to predict the occurrence, chemotherapy response and prognosis of NSCLC.
|
23524567 |
2013 |
|
Sarcoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
A common single nucleotide polymorphism (SNP) Gly388Arg variant has been associated with increased tumor cell motility and progression of breast cancer, head and neck cancer and soft tissue sarcomas.
|
23226373 |
2012 |
|
Islet Cell Tumor
|
|
0.010 |
GeneticVariation
|
BEFREE |
The FGFR4-G388R single-nucleotide polymorphism alters pancreatic neuroendocrine tumor progression and response to mTOR inhibition therapy.
|
22986737 |
2012 |
|
Oropharynx (excludes nasopharynx)
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results propose FGFR4 profile, measured by the Gly388Arg genotype and expression, as a novel marker of prognosis in squamous cell carcinoma of the mouth and oropharynx.
|
23226373 |
2012 |
|
Cholelithiasis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Fibroblast growth factor receptor 4 Gly388Arg polymorphism associated with severity of gallstone disease in a Chinese population.
|
22535390 |
2012 |
|
Malignant Head and Neck Neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
A common single nucleotide polymorphism (SNP) Gly388Arg variant has been associated with increased tumor cell motility and progression of breast cancer, head and neck cancer and soft tissue sarcomas.
|
23226373 |
2012 |
|
Head and Neck Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
A common single nucleotide polymorphism (SNP) Gly388Arg variant has been associated with increased tumor cell motility and progression of breast cancer, head and neck cancer and soft tissue sarcomas.
|
23226373 |
2012 |
|
Well Differentiated Pancreatic Endocrine Tumor
|
|
0.010 |
GeneticVariation
|
BEFREE |
The FGFR4-G388R single-nucleotide polymorphism alters pancreatic neuroendocrine tumor progression and response to mTOR inhibition therapy.
|
22986737 |
2012 |
|
Sarcoma of soft tissue
|
|
0.010 |
GeneticVariation
|
BEFREE |
A common single nucleotide polymorphism (SNP) Gly388Arg variant has been associated with increased tumor cell motility and progression of breast cancer, head and neck cancer and soft tissue sarcomas.
|
23226373 |
2012 |
|
Squamous cell carcinoma of mouth
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results propose FGFR4 profile, measured by the Gly388Arg genotype and expression, as a novel marker of prognosis in squamous cell carcinoma of the mouth and oropharynx.
|
23226373 |
2012 |
|
Eclampsia
|
|
0.010 |
GeneticVariation
|
BEFREE |
For Gly388Arg polymorphism of FGFR4 we found no significant association between controls and PE patients.
|
21827571 |
2011 |
|
Diarrhoea predominant irritable bowel syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
Interaction tests of KLB rs17618244 with 3 nonsynonymous SNPs of fibroblast growth factor receptor 4 (FGFR4) revealed that rs1966265 (Val10Ile) and rs351855 (Gly388Arg) modulate rs1768244's association with colonic transit in IBS-D (P=.0025 and P=.0023, respectively).
|
21396369 |
2011 |