|
Impaired cognition
|
|
0.100 |
GeneticVariation
|
BEFREE |
<i>BDNF</i> gene Val66Met variation may be associated with cognitive deficits in T2DM, especially with delayed memory.
|
29423073 |
2018 |
|
Cognition Disorders
|
|
0.020 |
GeneticVariation
|
BEFREE |
<i>BDNF</i> gene Val66Met variation may be associated with cognitive deficits in T2DM, especially with delayed memory.
|
29423073 |
2018 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.030 |
GeneticVariation
|
BEFREE |
<i>BDNF</i> gene Val66Met variation may be associated with cognitive deficits in T2DM, especially with delayed memory.
|
29423073 |
2018 |
|
Post-Traumatic Stress Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
<i>Met</i> carriers for BDNF rs6265 are at higher risk of developing PTSD and also exhibit more severe PTSD symptoms than <i>Val/Val</i> homozygotes among flood survivors in China.
|
28589140 |
2017 |
|
Depressed mood
|
|
0.100 |
GeneticVariation
|
BEFREE |
5-HTTLPR and BDNF VAL66MET, functional polymorphisms of the serotonin (5-HT) transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene, impact on two distinct, but interacting signaling systems, which have been related to depression and to the modulation of neurogenesis and plasticity of circuitries of emotion processing.
|
18347599 |
2008 |
|
Depressive disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
5-HTTLPR and BDNF VAL66MET, functional polymorphisms of the serotonin (5-HT) transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene, impact on two distinct, but interacting signaling systems, which have been related to depression and to the modulation of neurogenesis and plasticity of circuitries of emotion processing.
|
18347599 |
2008 |
|
Mental Depression
|
|
0.100 |
GeneticVariation
|
BEFREE |
5-HTTLPR and BDNF VAL66MET, functional polymorphisms of the serotonin (5-HT) transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene, impact on two distinct, but interacting signaling systems, which have been related to depression and to the modulation of neurogenesis and plasticity of circuitries of emotion processing.
|
18347599 |
2008 |
|
Rumination Disorders
|
|
0.040 |
GeneticVariation
|
BEFREE |
Rumination may be an endophenotype in the pathway from the BDNF Val66Met polymorphism to depression.
|
17959306 |
2007 |
|
Sleeplessness
|
|
0.030 |
GeneticVariation
|
BEFREE |
Insomnia and decreased sexual desire, side effects of fluoxetine, may have an association with the BDNF Val66Met polymorphism, and Met allele carriers showed a lower incidence of these side effects.
|
20016225 |
2010 |
|
child abuse behavior
|
|
0.020 |
GeneticVariation
|
BEFREE |
Child abuse may moderate Val66Met's impact on threat reactivity.
|
29649711 |
2018 |
|
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Val66Met polymorphism of the BDNF gene may be associated with cognitive performance on the WCST in bipolar mood disorder but not in schizophrenia.
|
16472361 |
2006 |
|
Schizophrenia
|
|
0.100 |
GeneticVariation
|
BEFREE |
Val66Met polymorphism of the BDNF gene may be associated with cognitive performance on the WCST in bipolar mood disorder but not in schizophrenia.
|
16472361 |
2006 |
|
Mental disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
G196A, a common polymorphism of the BDNF gene, not only affects cognitive and motor processes, but also is associated with various psychiatric disorders.
|
20085561 |
2010 |
|
Abnormal behavior
|
|
0.100 |
GeneticVariation
|
BEFREE |
G196A, a common polymorphism of the BDNF gene, not only affects cognitive and motor processes, but also is associated with various psychiatric disorders.
|
20085561 |
2010 |
|
Parkinson Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
G196A polymorphism is not a risk factor for PD and does not seem to modify clinical features in PD patients studied here.
|
20085561 |
2010 |
|
Melancholia
|
|
0.030 |
GeneticVariation
|
BEFREE |
Val66Met BDNF genotypes in melancholic depression: effects on brain structure and treatment outcome.
|
23165919 |
2013 |
|
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Val66Met polymorphism and serum brain-derived neurotrophic factor in bipolar disorder: an open-label trial.
|
23957567 |
2014 |
|
Acute Cerebrovascular Accidents
|
|
0.020 |
GeneticVariation
|
BEFREE |
Val66Met BDNF gene polymorphism influences human motor cortex plasticity in acute stroke.
|
25241287 |
2015 |
|
Dystonia
|
|
0.030 |
GeneticVariation
|
BEFREE |
Val66Met polymorphism of brain-derived neurotrophic factor is associated with idiopathic dystonia.
|
25523127 |
2015 |
|
Dystonia Disorders
|
|
0.030 |
GeneticVariation
|
BEFREE |
Val66Met polymorphism of brain-derived neurotrophic factor is associated with idiopathic dystonia.
|
25523127 |
2015 |
|
Obsessive-Compulsive Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Val66Met variation was not associated with OCD or GAD.
|
26209750 |
2015 |
|
Generalized Anxiety Disorder
|
|
0.050 |
GeneticVariation
|
BEFREE |
Val66Met variation was not associated with OCD or GAD.
|
26209750 |
2015 |
|
Mental disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Val66Met (also known as rs6265 or G196A), the only known functional polymorphism of the BDNF gene, has been widely studied and considered to be associated with risk of some psychiatric disorders such as bipolar disorder and schizophrenia.
|
26503495 |
2015 |
|
Abnormal behavior
|
|
0.100 |
GeneticVariation
|
BEFREE |
Val66Met (also known as rs6265 or G196A), the only known functional polymorphism of the BDNF gene, has been widely studied and considered to be associated with risk of some psychiatric disorders such as bipolar disorder and schizophrenia.
|
26503495 |
2015 |
|
Schizophrenia
|
|
0.100 |
GeneticVariation
|
BEFREE |
Val66Met (also known as rs6265 or G196A), the only known functional polymorphism of the BDNF gene, has been widely studied and considered to be associated with risk of some psychiatric disorders such as bipolar disorder and schizophrenia.
|
26503495 |
2015 |