|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
|
18193044 |
2008 |
|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
|
18193044 |
2008 |
|
Serum LDL cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
|
18193044 |
2008 |
|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
SNPs rs599839 and rs646776 both explained around 1% of the variation in circulating LDL-cholesterol concentrations and were associated with about 15% of an SD change in LDL cholesterol per allele, assuming an SD of 1 mmol/L.
|
18262040 |
2008 |
|
Serum LDL cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
SNPs rs599839 and rs646776 both explained around 1% of the variation in circulating LDL-cholesterol concentrations and were associated with about 15% of an SD change in LDL cholesterol per allele, assuming an SD of 1 mmol/L.
|
18262040 |
2008 |
|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|
19060910 |
2009 |
|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|
19060910 |
2009 |
|
Serum LDL cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|
19060910 |
2009 |
|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
|
19060911 |
2009 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
|
19060911 |
2009 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
|
19060911 |
2009 |
|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
|
19060911 |
2009 |
|
Serum LDL cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
|
19060911 |
2009 |
|
Myocardial Infarction
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
|
19198609 |
2009 |
|
Myocardial Infarction
|
|
0.810 |
GeneticVariation
|
GWASDB |
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
|
19198609 |
2009 |
|
Lipids measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
|
19936222 |
2009 |
|
Carotid Artery Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that two loci, chromosome 1p13.3 near CELSR2 and PSRC1 which contains rs646776, and 19q13.2 near TOMM40 and APOE which contains rs2075650, harbor risk alleles for CAAD.
|
19951432 |
2009 |
|
Frontotemporal Lobar Degeneration
|
|
0.010 |
GeneticVariation
|
BEFREE |
The association of rs646776 with plasma GRN levels was replicated in two independent series of 508 controls (p = 1.9 × 10⁻¹⁹) and 197 FTLD patients (p = 6.4 × 10⁻¹²).
|
21087763 |
2010 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.
|
21239051 |
2011 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|
21347282 |
2011 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASCAT |
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.
|
21378988 |
2011 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASDB |
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.
|
21378988 |
2011 |
|
Pseudocholinesterase Measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.
|
21943158 |
2011 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric analysis identifies novel variants for coronary artery disease.
|
21966275 |
2011 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
Five single-nucleotide polymorphisms, rs4977574 (CDKN2A/2B), rs12526453 (PHACTR1), rs646776 (CELSR2-PSRC1-SORT1), rs2259816 (HNF1A), and rs11206510 (PCSK9) showed directionally consistent associations with CHD in the 3 studies, with combined odds ratios (ORs) ranging from 1.17 to 1.25 (p = 0.03 to 0.0002).
|
22152955 |
2011 |