|
Thyroid carcinoma
|
|
0.860 |
GeneticVariation
|
GWASCAT |
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.
|
19198613 |
2009 |
|
Thyroid carcinoma
|
|
0.860 |
GeneticVariation
|
GWASDB |
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.
|
19198613 |
2009 |
|
Thyroid carcinoma
|
|
0.860 |
GeneticVariation
|
GWASDB |
The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.
|
20350937 |
2010 |
|
Thyroid carcinoma
|
|
0.860 |
GeneticVariation
|
GWASCAT |
The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.
|
20350937 |
2010 |
|
Nasopharyngeal carcinoma
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.
|
20512145 |
2010 |
|
Hypothyroidism
|
|
0.700 |
GeneticVariation
|
GWASDB |
Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies.
|
21981779 |
2011 |
|
Papillary thyroid carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association of both rs965513 (p=1.27×10(-4), OR=1.69, 95% CI 1.29 to 2.21) and rs944289 (p=0.0121, OR=1.21, 95% CI 1.04 to 1.39) with the risk of sporadic PTC was confirmed.
|
21730105 |
2011 |
|
Thyroid carcinoma
|
|
0.860 |
GeneticVariation
|
BEFREE |
The four validated TC SNPs accounted for a relatively large proportion (∼11%) of the sibling relative risk of TC, principally owing to the large effect size of rs965513 (OR 1.74).
|
22282540 |
2012 |
|
Thyroid carcinoma
|
|
0.860 |
GeneticVariation
|
BEFREE |
Of those, rs965513 has previously been shown to associate with thyroid cancer.
|
22267200 |
2012 |
|
Thyroid carcinoma
|
|
0.860 |
GeneticVariation
|
GWASDB |
Of those, rs965513 has previously been shown to associate with thyroid cancer.
|
22267200 |
2012 |
|
Hypothyroidism
|
|
0.700 |
GeneticVariation
|
GWASDB |
Novel associations for hypothyroidism include known autoimmune risk loci.
|
22493691 |
2012 |
|
Polysomnography
|
|
0.700 |
GeneticVariation
|
GWASDB |
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
|
23251661 |
2012 |
|
Papillary thyroid carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
A genome-wide association study of papillary thyroid carcinoma (PTC) pinpointed two independent SNPs (rs944289 and rs965513) located in regions containing no annotated genes (14q13.3 and 9q22.33, respectively).
|
22586128 |
2012 |
|
Malignant neoplasm of thyroid
|
|
0.060 |
GeneticVariation
|
BEFREE |
Of those, rs965513 has previously been shown to associate with thyroid cancer.
|
22267200 |
2012 |
|
Thyroid Neoplasm
|
|
0.060 |
GeneticVariation
|
BEFREE |
Of those, rs965513 has previously been shown to associate with thyroid cancer.
|
22267200 |
2012 |
|
Malignant neoplasm of thyroid
|
|
0.060 |
GeneticVariation
|
BEFREE |
The four validated TC SNPs accounted for a relatively large proportion (∼11%) of the sibling relative risk of TC, principally owing to the large effect size of rs965513 (OR 1.74).
|
22282540 |
2012 |
|
Thyroid Neoplasm
|
|
0.060 |
GeneticVariation
|
BEFREE |
The four validated TC SNPs accounted for a relatively large proportion (∼11%) of the sibling relative risk of TC, principally owing to the large effect size of rs965513 (OR 1.74).
|
22282540 |
2012 |
|
Familial (FPAH)
|
|
0.010 |
GeneticVariation
|
BEFREE |
In particular, two reported risk variants were associated with the disease: rs965513 (allele A) with familial (OR = 2·30, 95% CI = 1·48-3·59, P = 0·0002) and sporadic (OR = 2·81, 95% CI = 1·87-4·22, P < 0·0001) NMTC and rs1867277 (allele A) with the sporadic (OR = 1·76, 95% CI = 1·18-2·62, P = 0·0052) and combined NMTC cases (OR = 1·70, 95% CI = 1·21-2·40, P = 0·0022).
|
22882326 |
2012 |
|
Nonmedullary Thyroid Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In particular, two reported risk variants were associated with the disease: rs965513 (allele A) with familial (OR = 2·30, 95% CI = 1·48-3·59, P = 0·0002) and sporadic (OR = 2·81, 95% CI = 1·87-4·22, P < 0·0001) NMTC and rs1867277 (allele A) with the sporadic (OR = 1·76, 95% CI = 1·18-2·62, P = 0·0052) and combined NMTC cases (OR = 1·70, 95% CI = 1·21-2·40, P = 0·0022).
|
22882326 |
2012 |
|
Thyroid carcinoma
|
|
0.860 |
GeneticVariation
|
GWASCAT |
Genome-wide association study on differentiated thyroid cancer.
|
23894154 |
2013 |
|
Thyroid carcinoma
|
|
0.860 |
GeneticVariation
|
GWASDB |
Genome-wide association study on differentiated thyroid cancer.
|
23894154 |
2013 |
|
Thyroid carcinoma
|
|
0.860 |
GeneticVariation
|
BEFREE |
Five single nucleotide polymorphisms (SNPs) were previously reported to be associated with thyroid cancer in European populations in two genome-wide association studies (GWAS): rs965513 (9q22.33), rs944289 (14q13.3), rs116909374 (14q13.3), rs966423 (2q35) and rs2439302 (8p12).
|
23847140 |
2013 |
|
Papillary thyroid carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Four candidate loci, rs965513 (9q22.33), rs944289 (14q13.3), rs966423 (2q35) and rs2439302 (8p12), identified by GWAS for PTC risk were confirmed in a Chinese population.
|
23847140 |
2013 |
|
Thyroid Neoplasm
|
|
0.060 |
GeneticVariation
|
BEFREE |
Five single nucleotide polymorphisms (SNPs) were previously reported to be associated with thyroid cancer in European populations in two genome-wide association studies (GWAS): rs965513 (9q22.33), rs944289 (14q13.3), rs116909374 (14q13.3), rs966423 (2q35) and rs2439302 (8p12).
|
23847140 |
2013 |
|
Malignant neoplasm of thyroid
|
|
0.060 |
GeneticVariation
|
BEFREE |
Five single nucleotide polymorphisms (SNPs) were previously reported to be associated with thyroid cancer in European populations in two genome-wide association studies (GWAS): rs965513 (9q22.33), rs944289 (14q13.3), rs116909374 (14q13.3), rs966423 (2q35) and rs2439302 (8p12).
|
23847140 |
2013 |