Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SLC66A3 Q8N755 solute carrier family 66 member 3 4.4E-10 0.890 0.115 3
ACOT12 Q8WYK0 acyl-CoA thioesterase 12 Enzyme 2.7E-14 0.805 0.192 4
ALDOC P09972 aldolase, fructose-bisphosphate C 9.2E-02 0.780 0.231 6
PPP1R9A Q9ULJ8 protein phosphatase 1 regulatory subunit 9A 1.1E-05 0.769 0.269 7
GMPS P49915 guanine monophosphate synthase Enzyme 1.00 0.769 0.269 6
IQGAP2 Q13576 IQ motif containing GTPase activating protein 2 Enzyme modulator 8.5E-27 0.674 0.269 5
ING3 Q9NXR8 inhibitor of growth family member 3 1.00 0.695 0.269 5
UACA Q9BZF9 uveal autoantigen with coiled-coil domains and ankyrin repeats 3.2E-29 0.780 0.269 5
PFAS O15067 phosphoribosylformylglycinamidine synthase 9.9E-18 0.780 0.308 6
MCM9 Q9NXL9 minichromosome maintenance 9 homologous recombination repair factor Enzyme 6.6E-14 0.716 0.346 5
PPAT Q06203 phosphoribosyl pyrophosphate amidotransferase Enzyme 0.99 0.705 0.385 7
MTHFD2 P13995 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Enzyme 2.4E-03 0.666 0.423 5
GNMT Q14749 glycine N-methyltransferase 2.8E-03 0.626 0.462 7
SAV1 Q9H4B6 salvador family WW domain containing protein 1 9.0E-04 0.659 0.500 6
SHC1 P29353 SHC adaptor protein 1 Signaling 1.7E-03 0.597 0.538 9
NFE2L1 Q14494 nuclear factor, erythroid 2 like 1 Enzyme 1.00 0.678 0.538 6
ABCB4 P21439 ATP binding cassette subfamily B member 4 Transporter 2.2E-07 0.529 0.615 10
CAPN3 P20807 calpain 3 Enzyme 3.6E-19 0.564 0.615 8
HNRNPD Q14103 heterogeneous nuclear ribonucleoprotein D 1.00 0.621 0.654 6
MCM7 P33993 minichromosome maintenance complex component 7 Enzyme 1.9E-24 0.572 0.654 6
ASIP P42127 agouti signaling protein Signaling 1.6E-02 0.584 0.692 11
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692 11
RGN Q15493 regucalcin Enzyme 2.2E-02 0.566 0.692 8
CARM1 Q86X55 coactivator associated arginine methyltransferase 1 Epigenetic regulator 1.00 0.601 0.692 7