Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 69 3
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 119 20
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 241 7
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 69 0
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 81 2
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 115 6
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 43 12
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 82 6
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 73 19
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 97 0
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885 104 0
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 90 362
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 39 72
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885 36 44
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 75 6
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923 32 0
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 85 5
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 133 7
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846 78 18
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846 23 30
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 107 2
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 115 1
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 109 0