Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 241 7
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 133 7
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 119 20
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 115 6
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 115 1
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 109 4
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 109 0
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923 108 98
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 107 2
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885 104 0
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577 102 7
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 97 0
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 93 1
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 90 362
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 85 5
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 82 6
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 81 2
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846 78 18
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 75 6
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 73 19
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 69 3
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 69 0
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769 68 4