Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CYTB P00156 cytochrome b 0.529 0.808 9
ADH1C P00326 alcohol dehydrogenase 1C (class I), gamma polypeptide Enzyme 0.547 0.731 1
SLC12A3 P55017 solute carrier family 12 member 3 Transporter 3.0E-32 0.493 0.808 2
SELP P16109 selectin P 5.0E-32 0.460 0.769 12
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885 3
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885 13
ITGB6 P18564 integrin subunit beta 6 Receptor 1.6E-22 0.597 0.692 3
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923 5
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923 17
CYP3A5 P20815 cytochrome P450 family 3 subfamily A member 5 Enzyme 6.3E-17 0.511 0.846 11
SELENBP1 Q13228 selenium binding protein 1 Immune response 3.2E-16 0.493 0.846 1
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 60
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 24
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846 10
ENTPD2 Q9Y5L3 ectonucleoside triphosphate diphosphohydrolase 2 Enzyme 1.5E-14 0.760 0.269 2
CYP3A7 P24462 cytochrome P450 family 3 subfamily A member 7 6.1E-14 0.670 0.500 1
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846 7
IDUA P35475 alpha-L-iduronidase Enzyme 3.8E-13 0.499 0.846 4
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 9
IFI16 Q16666 interferon gamma inducible protein 16 Transcription factor 1.8E-11 0.603 0.769 1
GSN P06396 gelsolin Cellular structure 3.9E-11 0.475 0.885 4
HTR2B P41595 5-hydroxytryptamine receptor 2B G-protein coupled receptor 2.7E-10 0.647 0.538 7
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846 8
SLC66A3 Q8N755 solute carrier family 66 member 3 4.4E-10 0.890 0.115 3