Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2132 21
IFNG P01579 interferon gamma 0.47 0.288 0.962 1361 10
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1214 67
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1156 29
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1050 26
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923 1029 4
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 715 13
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 663 1
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846 557 3
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 552 2
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 517 111
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 477 9
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769 408 14
LMNA P02545 lamin A/C 1.00 0.384 0.885 401 107
FOXO1 Q12778 forkhead box O1 1.00 0.433 0.846 358 11
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808 348 10
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846 334 8
UVRAG Q9P2Y5 UV radiation resistance associated 0.99 0.436 0.769 334 3
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731 332 4
GLI1 P08151 GLI family zinc finger 1 7.7E-14 0.431 0.846 313 11
POU5F1 Q01860 POU class 5 homeobox 1 0.95 0.441 0.846 300 14
BMI1 P35226 BMI1 proto-oncogene, polycomb ring finger 0.94 0.448 0.808 293 0
NES P48681 nestin 1.6E-06 0.450 0.808 285 4