Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2245 232
IL6 P05231 interleukin 6 0.32 0.248 0.962 2132 21
IFNG P01579 interferon gamma 0.47 0.288 0.962 1361 10
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 1308 143
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1214 67
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1156 29
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1050 26
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923 1029 4
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 1011 29
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 999 26
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 957 6
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 942 62
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 888 48
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 839 55
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 715 13
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 706 18
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846 669 28
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 663 1
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 627 41
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 584 17
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846 557 3
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 553 32
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 552 2