Source: GWASDB

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 4 4
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 1 1
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 18 140
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 22 36
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 30 202
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 6 3
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885 14 12
CD40 P25942 CD40 molecule 0.85 0.396 0.846 8 5
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 2 7
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846 23 65
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 13 4
POU5F1 Q01860 POU class 5 homeobox 1 0.95 0.441 0.846 15 14
ITGAM P11215 integrin subunit alpha M 3.3E-11 0.443 0.808 3 9
ETS1 P14921 ETS proto-oncogene 1, transcription factor Transcription factor 0.78 0.444 0.731 7 4
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808 6 4
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808 1 1
ATG5 Q9H1Y0 autophagy related 5 Transporter 0.98 0.462 0.885 8 7
MST1 P26927 macrophage stimulating 1 Enzyme 4.8E-19 0.465 0.885 6 1
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769 11 20
STAT4 Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 0.77 0.471 0.769 13 17
IFIH1 Q9BYX4 interferon induced with helicase C domain 1 7.0E-44 0.471 0.808 4 1
TNFAIP3 P21580 TNF alpha induced protein 3 Enzyme 1.00 0.481 0.808 5 7
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 32 28
CD86 P42081 CD86 molecule 0.95 0.483 0.769 1 2