Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
AGPAT1 Q99943 1-acylglycerol-3-phosphate O-acyltransferase 1 0.97 0.743 0.423 18 13
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 194 9
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 399 8
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769 216 12
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 154 15
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 77 0
HPD P32754 4-hydroxyphenylpyruvate dioxygenase Enzyme 5.3E-04 0.573 0.769 102 9
NT5DC3 Q86UY8 5'-nucleotidase domain containing 3 Enzyme 1.5E-07 0.821 0.192 9 4
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 376 7
NT5C1A Q9BXI3 5'-nucleotidase, cytosolic IA 8.3E-05 0.615 0.654 63 1
NT5C3A Q9H0P0 5'-nucleotidase, cytosolic IIIA Enzyme 1.5E-02 0.593 0.692 80 15
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 140 9
HTR1D P28221 5-hydroxytryptamine receptor 1D G-protein coupled receptor 6.4E-04 0.716 0.308 26 1
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 245 30
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 207 22
PFKFB4 Q16877 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Enzyme 2.1E-09 0.666 0.346 40 3
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 313 38
ABHD11-AS1 ABHD11 antisense RNA 1 (tail to tail) 0.722 0.192 24 1
ASPM Q8IZT6 abnormal spindle microtubule assembly 3.4E-49 0.526 0.769 159 165
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 443 160
AIM2 O14862 absent in melanoma 2 2.2E-09 0.521 0.769 167 15
ACP3 P15309 acid phosphatase 3 Enzyme 2.5E-16 0.525 0.731 151 0
ANP32A P39687 acidic nuclear phosphoprotein 32 family member A Enzyme modulator 0.99 0.674 0.577 47 2
ANP32B Q92688 acidic nuclear phosphoprotein 32 family member B Enzyme modulator 0.96 0.541 0.731 120 2