CDK12 |
Q9NYV4
|
cyclin dependent kinase 12
|
Kinase
|
1.00 |
0.638 |
0.462 |
4
|
RRAS2 |
P62070
|
RAS related 2
|
Enzyme modulator
|
0.97 |
0.656 |
0.500 |
4
|
RNF43 |
Q68DV7
|
ring finger protein 43
|
|
0.73 |
0.584 |
0.577 |
10
|
PMS1 |
P54277
|
PMS1 homolog 1, mismatch repair system component
|
Nucleic acid binding
|
1.3E-17 |
0.569 |
0.654 |
8
|
OPCML |
Q14982
|
opioid binding protein/cell adhesion molecule like
|
|
0.23 |
0.606 |
0.654 |
4
|
MSH6 |
P52701
|
mutS homolog 6
|
Nucleic acid binding
|
3.7E-05 |
0.462 |
0.731 |
8
|
CCNE1 |
P24864
|
cyclin E1
|
Enzyme modulator
|
0.97 |
0.538 |
0.731 |
5
|
AKT2 |
P31751
|
AKT serine/threonine kinase 2
|
Kinase
|
0.64 |
0.474 |
0.769 |
15
|
STK11 |
Q15831
|
serine/threonine kinase 11
|
Kinase
|
0.99 |
0.435 |
0.808 |
17
|
MLH1 |
P40692
|
mutL homolog 1
|
Nucleic acid binding
|
3.4E-05 |
0.399 |
0.808 |
12
|
PMS2 |
P54278
|
PMS1 homolog 2, mismatch repair system component
|
Nucleic acid binding
|
4.5E-27 |
0.484 |
0.808 |
10
|
MSH2 |
P43246
|
mutS homolog 2
|
Nucleic acid binding
|
0.90 |
0.406 |
0.808 |
8
|
ERCC6 |
P0DP91 Q03468
|
ERCC excision repair 6, chromatin remodeling factor
|
|
5.2E-22 |
0.507 |
0.808 |
4
|
BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
45
|
BRCA2 |
P51587
|
BRCA2 DNA repair associated
|
Nucleic acid binding
|
2.4E-25 |
0.379 |
0.846 |
16
|
MAP2K1 |
Q02750
|
mitogen-activated protein kinase kinase 1
|
Kinase
|
0.90 |
0.439 |
0.846 |
10
|
ERCC4 |
Q92889
|
ERCC excision repair 4, endonuclease catalytic subunit
|
Enzyme
|
1.4E-12 |
0.468 |
0.846 |
8
|
CTNNB1 |
P35222
|
catenin beta 1
|
|
1.00 |
0.303 |
0.885 |
23
|
PIK3R1 |
P27986
|
phosphoinositide-3-kinase regulatory subunit 1
|
Kinase
|
1.00 |
0.477 |
0.885 |
8
|
SMARCA4 |
P51532
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
|
Epigenetic regulator
|
1.00 |
0.450 |
0.885 |
6
|
KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
33
|
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
33
|
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
27
|
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
22
|