Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 59
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885 13
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 40
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885 30
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885 18
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 25
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 17
TLR9 Q9NR96 toll like receptor 9 9.8E-06 0.411 0.885 3
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 9
DHODH Q02127 dihydroorotate dehydrogenase (quinone) Enzyme 3.0E-03 0.576 0.769 5
IL5 P05113 interleukin 5 5.7E-03 0.437 0.846 14
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 18
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 16
HAVCR2 Q8TDQ0 hepatitis A virus cellular receptor 2 3.9E-02 0.450 0.808 4
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 27
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846 7
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 26
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
CD28 P10747 CD28 molecule 0.36 0.436 0.885 3
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731 12
RHOA P61586 ras homolog family member A Enzyme modulator 0.60 0.502 0.808 14
CD59 P13987 CD59 molecule (CD59 blood group) 0.61 0.469 0.808 11