Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 12
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769 30
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 17
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 19
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
CFL1 P23528 cofilin 1 0.56 0.529 0.769 14
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 11
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808 6
DYNLL1 P63167 dynein light chain LC8-type 1 Cellular structure 0.70 0.568 0.769 7
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 48
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885 17
FABP4 P15090 fatty acid binding protein 4 5.2E-05 0.500 0.808 3
GRK2 P25098 G protein-coupled receptor kinase 2 Kinase 1.00 0.532 0.654 15
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 28
HDAC3 O15379 histone deacetylase 3 Epigenetic regulator 0.57 0.511 0.731 6
IGFBP3 P17936 insulin like growth factor binding protein 3 Enzyme modulator 0.91 0.439 0.808 8
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 20
MCAM P43121 melanoma cell adhesion molecule Cell adhesion 1.6E-04 0.514 0.731 6
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 46