Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ATF1 P18846 activating transcription factor 1 0.63 0.588 0.577 1
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846 25
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
ANKS6 Q68DC2 ankyrin repeat and sterile alpha motif domain containing 6 6.9E-06 0.682 0.346 1
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 39
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846 13
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846 22
CTSH P09668 cathepsin H Enzyme 1.3E-08 0.626 0.654 2
C9 P02748 complement C9 1.6E-24 0.619 0.692 1
CFB P00751 complement factor B 4.7E-16 0.532 0.769 2
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769 15
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731 12
GPBAR1 Q8TDU6 G protein-coupled bile acid receptor 1 G-protein coupled receptor 1.4E-09 0.548 0.731 1
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 1
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846 3
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 45
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846 8
LRP5 O75197 LDL receptor related protein 5 0.51 0.485 0.846 4
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 25
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808 20
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 69
PITX2 Q99697 paired like homeodomain 2 0.98 0.489 0.808 2
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 27