Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923 72
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 64
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 39
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 34
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808 34
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 31
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808 15
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 13
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692 13
PRKDC P78527 protein kinase, DNA-activated, catalytic subunit Kinase 1.00 0.540 0.808 10
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808 6
NUP98 P52948 nucleoporin 98 and 96 precursor Enzyme 1.00 0.532 0.577 5
NCOA2 Q15596 nuclear receptor coactivator 2 Enzyme 1.00 0.575 0.615 4
HIPK2 Q9H2X6 homeodomain interacting protein kinase 2 Kinase 1.00 0.566 0.731 4
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 4
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731 3
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 3
HCFC1 P51610 host cell factor C1 1.00 0.601 0.692 2
HTT P42858 huntingtin 1.00 0.548 0.654 2
NUMA1 Q14980 nuclear mitotic apparatus protein 1 1.00 0.644 0.577 2
NSD2 O96028 nuclear receptor binding SET domain protein 2 Epigenetic regulator 1.00 0.507 0.769 2
KAT6A Q92794 lysine acetyltransferase 6A Enzyme 1.00 0.560 0.769 2
MLLT10 P55197 MLLT10 histone lysine methyltransferase DOT1L cofactor Transcription factor 1.00 0.551 0.462 2
RBM6 P78332 RNA binding motif protein 6 1.00 0.722 0.385 1