Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MAGEA3 P43357 MAGE family member A3 Cell adhesion 0.588 0.500 9
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 3
HOXA@ homeobox A cluster 0.599 0.654 2
KIR2DS5 Q14953 killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5 Receptor 0.678 0.500 2
XRCC6P3 X-ray repair cross complementing 6 pseudogene 3 1.000 0.038 1
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 32
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 94
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 25
SLC22A16 Q86VW1 solute carrier family 22 member 16 Transporter 6.3E-27 0.626 0.500 3
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885 16
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 17
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808 17
AKR1C3 P42330 aldo-keto reductase family 1 member C3 Enzyme 7.6E-24 0.529 0.769 8
ALOX15 P16050 arachidonate 15-lipoxygenase Enzyme 1.1E-23 0.502 0.846 15
FANCL Q9NW38 FA complementation group L Enzyme 5.9E-23 0.551 0.731 3
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846 14
HMMR O75330 hyaluronan mediated motility receptor 5.5E-21 0.544 0.615 9
NOX4 Q9NPH5 NADPH oxidase 4 Enzyme 5.8E-20 0.471 0.885 7
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846 20
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846 40
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 149
CYP3A5 P20815 cytochrome P450 family 3 subfamily A member 5 Enzyme 6.3E-17 0.511 0.846 5
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808 17
PADI4 Q9UM07 peptidyl arginine deiminase 4 4.6E-16 0.494 0.808 6