Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NCAPH Q15003 non-SMC condensin I complex subunit H 8.0E-05 0.760 0.385 1
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769 2
IARS1 P41252 isoleucyl-tRNA synthetase 1 Enzyme 1.7E-21 0.606 0.692 2
SLC9A6 Q92581 solute carrier family 9 member A6 Transporter 1.00 0.516 0.846 2
UFC1 Q9Y3C8 ubiquitin-fold modifier conjugating enzyme 1 3.6E-03 0.716 0.462 2
UFM1 P61960 ubiquitin fold modifier 1 0.16 0.722 0.385 2
ZNHIT3 Q15649 zinc finger HIT-type containing 3 5.5E-07 0.666 0.462 2
AGMO Q6ZNB7 alkylglycerol monooxygenase 6.8E-26 0.780 0.423 3
CCDC88A Q3V6T2 coiled-coil domain containing 88A Enzyme modulator 1.00 0.610 0.615 3
GPT2 Q8TD30 glutamic--pyruvic transaminase 2 Enzyme 3.4E-04 0.650 0.577 3
NUP214 P35658 nucleoporin 214 Nucleic acid binding 5.5E-02 0.638 0.385 3
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885 4
CARS1 P49589 cysteinyl-tRNA synthetase 1 Enzyme 4.0E-04 0.722 0.538 4
CEP63 Q96MT8 centrosomal protein 63 Cellular structure 6.2E-25 0.666 0.500 4
DYNC1I2 Q13409 dynein cytoplasmic 1 intermediate chain 2 Cellular structure 1.1E-08 0.760 0.385 4
METTL5 Q9NRN9 methyltransferase like 5 5.2E-05 1.000 0.115 4
PCDH12 Q9NPG4 protocadherin 12 2.9E-13 0.722 0.346 4
PUS3 Q9BZE2 pseudouridine synthase 3 Enzyme 1.4E-08 0.780 0.346 4
CENPF P49454 centromere protein F 1.9E-36 0.601 0.654 5
CENPJ Q9HC77 centromere protein J Enzyme 2.1E-27 0.546 0.846 5
FARSB Q9NSD9 phenylalanyl-tRNA synthetase subunit beta Enzyme 3.3E-03 0.682 0.500 5
KIF14 Q15058 kinesin family member 14 Cellular structure 4.1E-05 0.578 0.654 5
TMX2 Q9Y320 thioredoxin related transmembrane protein 2 0.65 0.821 0.231 5
NSD2 O96028 nuclear receptor binding SET domain protein 2 Epigenetic regulator 1.00 0.507 0.769 6