Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SLC5A6 Q9Y289 solute carrier family 5 member 6 Transporter 6.1E-03 0.674 0.577 18
ATP1A2 P50993 ATPase Na+/K+ transporting subunit alpha 2 Transporter 1.8E-04 0.597 0.615 13
ZNF292 O60281 zinc finger protein 292 Enzyme 1.00 0.695 0.423 12
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846 11
ZMIZ1 Q9ULJ6 zinc finger MIZ-type containing 1 1.00 0.588 0.615 10
EIF2S3 P41091 eukaryotic translation initiation factor 2 subunit gamma Enzyme 0.96 0.604 0.731 9
GOT2 P00505 glutamic-oxaloacetic transaminase 2 1.4E-02 0.529 0.731 9
LSS P48449 lanosterol synthase 1.8E-07 0.606 0.654 9
STAG2 Q8N3U4 stromal antigen 2 Nucleic acid binding 1.00 0.568 0.731 7
TRAIP Q9BWF2 TRAF interacting protein 1.6E-05 0.644 0.654 7
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692 7
NSD2 O96028 nuclear receptor binding SET domain protein 2 Epigenetic regulator 1.00 0.507 0.769 6
NTNG2 Q96CW9 netrin G2 Enzyme modulator 1.00 0.700 0.423 6
PISD Q9UG56 phosphatidylserine decarboxylase 0.22 0.821 0.308 6
PUS7 Q96PZ0 pseudouridine synthase 7 1.3E-09 0.769 0.308 6
CENPF P49454 centromere protein F 1.9E-36 0.601 0.654 5
CENPJ Q9HC77 centromere protein J Enzyme 2.1E-27 0.546 0.846 5
FARSB Q9NSD9 phenylalanyl-tRNA synthetase subunit beta Enzyme 3.3E-03 0.682 0.500 5
KIF14 Q15058 kinesin family member 14 Cellular structure 4.1E-05 0.578 0.654 5
TMX2 Q9Y320 thioredoxin related transmembrane protein 2 0.65 0.821 0.231 5
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885 4
CARS1 P49589 cysteinyl-tRNA synthetase 1 Enzyme 4.0E-04 0.722 0.538 4
CEP63 Q96MT8 centrosomal protein 63 Cellular structure 6.2E-25 0.666 0.500 4
DYNC1I2 Q13409 dynein cytoplasmic 1 intermediate chain 2 Cellular structure 1.1E-08 0.760 0.385 4