TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
2245
|
232 |
BRCA1 |
P38398
|
BRCA1 DNA repair associated
|
Enzyme
|
9.2E-29 |
0.367 |
0.923 |
576
|
169 |
EGFR |
P00533
|
epidermal growth factor receptor
|
Kinase
|
0.37 |
0.295 |
0.885 |
1308
|
143 |
CFTR |
P13569
|
CF transmembrane conductance regulator
|
Ion channel
|
2.2E-58 |
0.424 |
0.885 |
365
|
133 |
APC |
P25054
|
APC regulator of WNT signaling pathway
|
|
1.00 |
0.373 |
0.962 |
517
|
111 |
APP |
P05067
|
amyloid beta precursor protein
|
Enzyme modulator
|
4.7E-02 |
0.422 |
0.846 |
384
|
105 |
KCNQ1 |
P51787
|
potassium voltage-gated channel subfamily Q member 1
|
Ion channel
|
4.5E-08 |
0.485 |
0.769 |
156
|
105 |
ESR1 |
P03372
|
estrogen receptor 1
|
Nuclear receptor
|
1.00 |
0.324 |
0.962 |
972
|
97 |
MLH1 |
P40692
|
mutL homolog 1
|
Nucleic acid binding
|
3.4E-05 |
0.399 |
0.808 |
446
|
90 |
BRCA2 |
P51587
|
BRCA2 DNA repair associated
|
Nucleic acid binding
|
2.4E-25 |
0.379 |
0.846 |
459
|
89 |
VWF |
P04275
|
von Willebrand factor
|
Enzyme modulator
|
3.2E-25 |
0.408 |
0.885 |
432
|
88 |
FGFR2 |
P21802
|
fibroblast growth factor receptor 2
|
Kinase
|
1.00 |
0.380 |
0.808 |
345
|
85 |
RET |
P07949
|
ret proto-oncogene
|
Kinase
|
1.00 |
0.392 |
0.885 |
453
|
81 |
MAPT |
P10636
|
microtubule associated protein tau
|
|
6.0E-03 |
0.446 |
0.923 |
256
|
74 |
CDKN2B-AS1 |
|
CDKN2B antisense RNA 1
|
|
|
0.491 |
0.769 |
161
|
72 |
ACE |
P12821
|
angiotensin I converting enzyme
|
Enzyme
|
1.0E-37 |
0.328 |
0.923 |
979
|
70 |
CDKN2A |
P42771 Q8N726
|
cyclin dependent kinase inhibitor 2A
|
|
0.39 |
0.300 |
0.885 |
1214
|
67 |
VDR |
P11473
|
vitamin D receptor
|
Nuclear receptor
|
1.7E-05 |
0.352 |
0.885 |
757
|
66 |
ATM |
Q13315
|
ATM serine/threonine kinase
|
Kinase
|
5.6E-47 |
0.374 |
0.885 |
563
|
65 |
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
942
|
62 |
MSH2 |
P43246
|
mutS homolog 2
|
Nucleic acid binding
|
0.90 |
0.406 |
0.808 |
404
|
62 |
PAH |
P00439
|
phenylalanine hydroxylase
|
|
6.4E-23 |
0.516 |
0.769 |
138
|
60 |
FTO |
Q9C0B1
|
FTO alpha-ketoglutarate dependent dioxygenase
|
|
8.4E-08 |
0.486 |
0.885 |
196
|
59 |
VEGFA |
P15692
|
vascular endothelial growth factor A
|
Signaling
|
2.4E-05 |
0.266 |
0.923 |
1737
|
58 |