Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 3
ARPC3 O15145 actin related protein 2/3 complex subunit 3 Cellular structure 0.22 0.839 0.154 1
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846 26
DBN1 Q16643 drebrin 1 Cellular structure 1.00 0.633 0.538 6
DDC P20711 dopa decarboxylase 3.8E-08 0.535 0.769 8
DLG1 Q12959 discs large MAGUK scaffold protein 1 Receptor 0.99 0.647 0.654 1
DLG4 P78352 discs large MAGUK scaffold protein 4 Receptor 1.00 0.595 0.654 3
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808 16
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 23
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885 20
FEZ1 Q99689 fasciculation and elongation protein zeta 1 0.75 0.666 0.500 1
GDF5 P43026 growth differentiation factor 5 Signaling 0.67 0.511 0.692 1
GJC2 Q5T442 gap junction protein gamma 2 Cell-cell junction 1.0E-02 0.593 0.692 1
GRK2 P25098 G protein-coupled receptor kinase 2 Kinase 1.00 0.532 0.654 15
GRK3 P35626 G protein-coupled receptor kinase 3 Kinase 0.71 0.621 0.731 5
GRK5 P34947 G protein-coupled receptor kinase 5 Kinase 0.68 0.588 0.769 2
GRK6 P43250 G protein-coupled receptor kinase 6 Kinase 4.9E-04 0.670 0.654 3
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 26
HCN3 Q9P1Z3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 Ion channel 2.6E-05 0.792 0.308 3
HSF1 Q00613 heat shock transcription factor 1 Transcription factor 0.75 0.507 0.769 12
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923 5
HSPA8 P11142 heat shock protein family A (Hsp70) member 8 1.00 0.553 0.808 9
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808 18
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 4