Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 283
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 341
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 191
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 342
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 153
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 330
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 266
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 91
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 229
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 381
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 216
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 307
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 224
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846 125
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 217
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 205
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 326
ELN P15502 elastin 2.1E-14 0.415 0.885 257
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 327
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885 147
FLNA P21333 filamin A 1.00 0.419 0.846 298
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846 123