Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846 325
FLNA P21333 filamin A 1.00 0.419 0.846 298
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 281
ELN P15502 elastin 2.1E-14 0.415 0.885 257
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 236
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 220
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 218
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 218
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 217
PEX6 Q13608 peroxisomal biogenesis factor 6 6.3E-06 0.547 0.731 212
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769 209
PEX1 O43933 peroxisomal biogenesis factor 1 1.1E-14 0.538 0.769 209
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 205
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846 200
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654 187
FLNB O75369 filamin B 6.1E-10 0.458 0.923 187
SMC1A Q14683 structural maintenance of chromosomes 1A 1.00 0.509 0.808 174
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808 171
SETBP1 Q9Y6X0 SET binding protein 1 1.00 0.503 0.808 160
WDR35 Q9P2L0 WD repeat domain 35 1.0E-22 0.525 0.692 160
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846 158
HBB P68871 hemoglobin subunit beta 1.2E-09 0.494 0.808 151
GPC4 O75487 glypican 4 0.93 0.547 0.769 150