Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923 72
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 39
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 34
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 31
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 19
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808 17
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808 15
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692 13
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 11
IGF2R P11717 insulin like growth factor 2 receptor Receptor 1.00 0.518 0.731 11
ROCK1 Q13464 Rho associated coiled-coil containing protein kinase 1 Kinase 1.00 0.513 0.731 11
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 10
TJP1 Q07157 tight junction protein 1 Cell-cell junction 1.00 0.576 0.692 10
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 9
MTA1 Q13330 metastasis associated 1 Nucleic acid binding 1.00 0.547 0.692 7
SLIT2 O94813 slit guidance ligand 2 1.00 0.511 0.769 7
HIPK2 Q9H2X6 homeodomain interacting protein kinase 2 Kinase 1.00 0.566 0.731 4
FUBP1 Q96AE4 far upstream element binding protein 1 Enzyme 1.00 0.610 0.615 3
KHSRP Q92945 KH-type splicing regulatory protein Enzyme 1.00 0.526 0.846 2
COPA P53621 COPI coat complex subunit alpha Transporter 1.00 0.700 0.385 1
CSE1L P55060 chromosome segregation 1 like Enzyme modulator 1.00 0.521 0.808 1
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 53
IGF2BP3 O00425 insulin like growth factor 2 mRNA binding protein 3 Enzyme 1.00 0.570 0.577 14
CTNND1 O60716 catenin delta 1 Cellular structure 1.00 0.500 0.808 11