Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MIR21 microRNA 21 0.363 0.846 726 2
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885 447 99
IFNB1 P01574 interferon beta 1 0.421 0.846 426 4
GRN P28799 granulin precursor 7.0E-02 0.435 0.846 412 66
GORASP1 Q9BQQ3 golgi reassembly stacking protein 1 2.0E-02 0.428 0.846 369 7
MMRN1 Q13201 multimerin 1 2.1E-25 0.465 0.846 272 3
MIR17 microRNA 17 0.459 0.846 270 2
GAP43 P17677 growth associated protein 43 2.1E-02 0.564 0.731 109 0
RAB7A P51149 RAB7A, member RAS oncogene family 0.97 0.597 0.692 95 5
CREB3L1 Q96BA8 cAMP responsive element binding protein 3 like 1 0.98 0.601 0.615 88 12
UCN3 Q969E3 urocortin 3 4.4E-02 0.593 0.731 82 0
CSPG4 Q6UVK1 chondroitin sulfate proteoglycan 4 2.6E-05 0.599 0.615 75 1
RAB7B Q96AH8 RAB7B, member RAS oncogene family 0.615 0.731 65 0
RGMA Q96B86 repulsive guidance molecule BMP co-receptor a 0.16 0.656 0.692 43 2
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 1349 384
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 1337 31
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 1234 27
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 1021 43
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 875 79
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 671 22
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846 304 17
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846 485 114
TG P01266 thyroglobulin Enzyme modulator 2.9E-59 0.480 0.808 240 43