Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CACNA1E Q15878 calcium voltage-gated channel subunit alpha1 E Ion channel 1.00 0.650 0.577 7
DDC P20711 dopa decarboxylase 3.8E-08 0.535 0.769 7
DDX6 P26196 DEAD-box helicase 6 1.00 0.663 0.385 7
DHPS P49366 deoxyhypusine synthase 1.6E-04 0.670 0.538 7
FCSK Q8N0W3 fucose kinase Kinase 1.0E-29 0.769 0.192 7
IQSEC1 Q6DN90 IQ motif and Sec7 domain ArfGEF 1 1.00 0.736 0.346 7
KAT8 Q9H7Z6 lysine acetyltransferase 8 0.22 0.592 0.654 7
KDM3B Q7LBC6 lysine demethylase 3B Epigenetic regulator 1.00 0.686 0.500 7
KDM5C P41229 lysine demethylase 5C 1.00 0.581 0.538 7
LNPK Q9C0E8 lunapark, ER junction formation factor 6.2E-04 0.716 0.346 7
PNPT1 Q8TCS8 polyribonucleotide nucleotidyltransferase 1 Enzyme 4.0E-04 0.653 0.462 7
PPP2CA P67775 protein phosphatase 2 catalytic subunit alpha 0.99 0.608 0.769 7
PUM1 Q14671 pumilio RNA binding family member 1 Nucleic acid binding 1.00 0.653 0.654 7
SMARCD1 Q96GM5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 Nucleic acid binding 1.00 0.695 0.385 7
SOX4 Q06945 SRY-box transcription factor 4 Transcription factor 0.93 0.489 0.808 7
STAG2 Q8N3U4 stromal antigen 2 Nucleic acid binding 1.00 0.568 0.731 7
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692 7
ZNF462 Q96JM2 zinc finger protein 462 Transcription factor 1.00 0.711 0.462 7
ACTL6B O94805 actin like 6B Cellular structure 2.8E-04 0.656 0.462 6
AP1B1 Q10567 adaptor related protein complex 1 subunit beta 1 Transporter 1.00 0.716 0.385 6
AP2M1 Q96CW1 adaptor related protein complex 2 subunit mu 1 Extracellular structure 1.00 0.751 0.231 6
CACNA2D2 Q9NY47 calcium voltage-gated channel auxiliary subunit alpha2delta 2 Ion channel 1.00 0.626 0.615 6
DIAPH1 O60610 diaphanous related formin 1 0.92 0.623 0.654 6
FBXW11 Q9UKB1 F-box and WD repeat domain containing 11 0.98 0.626 0.462 6