Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TLK2 Q86UE8 tousled like kinase 2 Kinase 1.00 0.631 0.538 2 3
ERN1 O75460 endoplasmic reticulum to nucleus signaling 1 Kinase 0.99 0.513 0.808 5 4
SPEG Q15772 striated muscle enriched protein kinase Kinase 0.92 0.686 0.385 3 4
EPHA2 P29317 EPH receptor A2 Kinase 1.1E-05 0.501 0.731 2 4
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692 5 5
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731 2 5
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846 6 6
GRK6 P43250 G protein-coupled receptor kinase 6 Kinase 4.9E-04 0.670 0.654 2 6
BMPR1B O00238 bone morphogenetic protein receptor type 1B Kinase 1.00 0.573 0.615 5 7
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731 3 7
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846 5 12
EPHB4 P54760 EPH receptor B4 Kinase 1.3E-02 0.524 0.692 4 13
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846 6 19
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 16 32
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 6 35
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 7 45