Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
CYTB P00156 cytochrome b 0.529 0.808 108 9
SI P14410 sucrase-isomaltase Enzyme 3.9E-60 0.569 0.692 108 4
ALDH7A1 P49419 aldehyde dehydrogenase 7 family member A1 Enzyme 1.4E-22 0.551 0.769 106 4
MGAM O43451 maltase-glucoamylase Enzyme 1.0E-35 0.592 0.615 89 9
AQP9 O43315 aquaporin 9 Ion channel 0.24 0.565 0.808 84 0
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731 83 1
FBP1 P09467 fructose-bisphosphatase 1 Enzyme 7.9E-02 0.575 0.692 81 2
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654 78 3
BCS1L Q9Y276 BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone 4.7E-13 0.534 0.808 77 2
HADHA P40939 hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha Enzyme 4.4E-06 0.569 0.769 61 2
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769 52 5
NDUFS4 O43181 NADH:ubiquinone oxidoreductase subunit S4 3.1E-04 0.587 0.808 52 1
KARS1 Q15046 lysyl-tRNA synthetase 1 Enzyme 4.2E-09 0.636 0.577 42 6
PDHA1 P08559 pyruvate dehydrogenase E1 subunit alpha 1 0.99 0.581 0.538 42 3
SURF1 Q15526 SURF1 cytochrome c oxidase assembly factor Enzyme 1.6E-13 0.578 0.654 38 1
WARS2 Q9UGM6 tryptophanyl tRNA synthetase 2, mitochondrial 5.1E-02 0.617 0.577 37 1
ECHS1 P30084 enoyl-CoA hydratase, short chain 1 Enzyme 8.8E-04 0.601 0.654 37 0
ND4 P03905 NADH dehydrogenase, subunit 4 (complex I) Enzyme 0.546 0.769 36 9
SLC37A4 O43826 solute carrier family 37 member 4 Transporter 1.7E-05 0.617 0.654 36 7
MTO1 Q9Y2Z2 mitochondrial tRNA translation optimization 1 7.4E-06 0.670 0.462 36 2
ELAC2 Q9BQ52 elaC ribonuclease Z 2 1.7E-20 0.670 0.346 32 11
PDP1 Q9P0J1 pyruvate dehyrogenase phosphatase catalytic subunit 1 Enzyme 0.45 0.691 0.462 32 1
ISCU Q9H1K1 iron-sulfur cluster assembly enzyme 4.1E-02 0.695 0.423 31 2
VARS2 Q5ST30 valyl-tRNA synthetase 2, mitochondrial 5.8E-17 0.666 0.577 28 9