Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2475 28
IL6 P05231 interleukin 6 0.32 0.248 0.962 2132 21
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1533 21
ALB P02768 albumin Transporter 0.64 0.317 0.962 1089 13
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 501 29
TTR P02766 transthyretin Transporter 0.52 0.423 0.885 404 48
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808 394 8
ABCB6 Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 8.6E-19 0.431 0.885 361 9
HSPA5 P11021 heat shock protein family A (Hsp70) member 5 0.77 0.434 0.885 324 9
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885 257 6
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885 255 19
LINC01194 long intergenic non-protein coding RNA 1194 0.470 0.769 249 0
SLC5A2 P31639 solute carrier family 5 member 2 Transporter 4.9E-14 0.499 0.769 209 7
SCO2 O43819 synthesis of cytochrome C oxidase 2 Enzyme 7.5E-07 0.479 0.846 194 4
TXNIP Q9H3M7 thioredoxin interacting protein 0.16 0.490 0.731 186 3
ATF4 P18848 activating transcription factor 4 1.6E-02 0.507 0.769 169 3
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846 167 28
PTBP1 P26599 polypyrimidine tract binding protein 1 1.00 0.517 0.769 162 3
DLD P09622 dihydrolipoamide dehydrogenase Enzyme 9.5E-03 0.517 0.769 156 11
CA2 P00918 carbonic anhydrase 2 1.7E-06 0.506 0.808 151 4
PC P11498 pyruvate carboxylase Enzyme 1.4E-02 0.515 0.808 149 4
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846 139 25
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846 122 2
MB P02144 myoglobin 3.1E-02 0.556 0.731 120 2