Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 877 101
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 875 79
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 873 39
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 859 12
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 854 163
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 852 81
LMNA P02545 lamin A/C 1.00 0.384 0.885 824 285
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 824 13
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 823 34
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 821 17
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 819 26
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 816 119
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 816 64
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 805 74
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 794 14
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 783 28
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 774 33
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 770 23
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 765 43
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 754 47
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 750 18
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 749 15
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 747 2600