Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MMP9 P14780 matrix metallopeptidase 9 hydrolase; protease 7.0E-18 0.339 0.862 60
CCL2 P13500 C-C motif chemokine ligand 2 signaling molecule 0.62 0.353 0.897 53
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 1.00 0.338 0.897 41
IL10 P22301 interleukin 10 6.5E-03 0.320 0.931 36
NOS2 P35228 nitric oxide synthase 2 1.5E-14 0.385 0.931 36
AGER Q15109 advanced glycosylation end-product specific receptor cell adhesion molecule; receptor 3.4E-16 0.472 0.724 33
SERPINE1 P05121 serpin family E member 1 enzyme modulator 4.7E-02 0.384 0.793 31
ICAM1 P05362 intercellular adhesion molecule 1 3.8E-02 0.386 0.897 30
CCL5 P13501 C-C motif chemokine ligand 5 signaling molecule 1.7E-03 0.429 0.793 24
TGFB1 P01137 transforming growth factor beta 1 signaling molecule 0.17 0.336 0.931 23
IL6 P05231 interleukin 6 0.34 0.287 0.966 21
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 nucleic acid binding; receptor; transcription factor 0.98 0.427 0.793 19
IL4 P05112 interleukin 4 5.3E-03 0.364 0.931 18
IL17A Q16552 interleukin 17A 4.4E-02 0.391 0.862 17
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.457 0.862 17
AGTR1 P30556 angiotensin II receptor type 1 receptor 5.7E-04 0.454 0.759 16
ESR2 Q92731 estrogen receptor 2 nucleic acid binding; receptor; transcription factor 5.4E-08 0.445 0.828 15
BDKRB2 P30411 bradykinin receptor B2 receptor 0.13 0.619 0.621 13
EDNRB P24530 endothelin receptor type B 1.2E-02 0.492 0.793 13
AGTR2 P50052 angiotensin II receptor type 2 receptor 8.2E-03 0.554 0.621 12
EGFR P00533 epidermal growth factor receptor 0.50 0.325 0.862 11
IL13 P35225 interleukin 13 1.3E-02 0.421 0.828 11
CCL11 P51671 C-C motif chemokine ligand 11 signaling molecule 9.8E-03 0.586 0.655 10
F7 P08709 coagulation factor VII hydrolase; protease 1.5E-05 0.547 0.690 10