BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
125
|
84 |
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
107
|
343 |
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
85
|
55 |
TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
84
|
390 |
TMEM94 |
Q12767
|
transmembrane protein 94
|
|
2.8E-14 |
0.628 |
0.654 |
73
|
2 |
HRAS |
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
8.0E-02 |
0.378 |
0.885 |
71
|
21 |
CTNNB1 |
P35222
|
catenin beta 1
|
|
1.00 |
0.303 |
0.885 |
70
|
52 |
GNAS |
O95467 P63092 P84996 Q5JWF2
|
GNAS complex locus
|
Enzyme modulator
|
0.68 |
0.420 |
0.885 |
60
|
27 |
ATM |
Q13315
|
ATM serine/threonine kinase
|
Kinase
|
5.6E-47 |
0.374 |
0.885 |
44
|
888 |
NRAS |
P01111
|
NRAS proto-oncogene, GTPase
|
Enzyme modulator
|
0.49 |
0.390 |
0.808 |
37
|
14 |
RET |
P07949
|
ret proto-oncogene
|
Kinase
|
1.00 |
0.392 |
0.885 |
36
|
77 |
APC |
P25054
|
APC regulator of WNT signaling pathway
|
|
1.00 |
0.373 |
0.962 |
33
|
582 |
FGFR1 |
P11362
|
fibroblast growth factor receptor 1
|
Kinase
|
1.00 |
0.362 |
0.885 |
27
|
63 |
MAP2K1 |
Q02750
|
mitogen-activated protein kinase kinase 1
|
Kinase
|
0.90 |
0.439 |
0.846 |
26
|
30 |
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
23
|
28 |
STK11 |
Q15831
|
serine/threonine kinase 11
|
Kinase
|
0.99 |
0.435 |
0.808 |
22
|
129 |
CDKN2A |
P42771 Q8N726
|
cyclin dependent kinase inhibitor 2A
|
|
0.39 |
0.300 |
0.885 |
22
|
83 |
CSF1R |
P07333
|
colony stimulating factor 1 receptor
|
Kinase
|
0.13 |
0.448 |
0.808 |
16
|
53 |
VHL |
P40337
|
von Hippel-Lindau tumor suppressor
|
Enzyme
|
8.0E-02 |
0.443 |
0.846 |
14
|
186 |
TSC2 |
P49815
|
TSC complex subunit 2
|
Enzyme modulator
|
1.00 |
0.439 |
0.808 |
13
|
244 |
ERBB3 |
P21860
|
erb-b2 receptor tyrosine kinase 3
|
Kinase
|
1.7E-15 |
0.448 |
0.808 |
12
|
7 |
RB1 |
P06400
|
RB transcriptional corepressor 1
|
Nucleic acid binding
|
1.00 |
0.444 |
0.885 |
11
|
224 |
PIK3R1 |
P27986
|
phosphoinositide-3-kinase regulatory subunit 1
|
Kinase
|
1.00 |
0.477 |
0.885 |
10
|
24 |
MYC |
P01106
|
MYC proto-oncogene, bHLH transcription factor
|
Transcription factor
|
1.00 |
0.344 |
0.923 |
6
|
8 |