Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 238
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 118
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 111
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 109
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 109
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923 106
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885 102
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 101
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 100
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 97
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 95
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577 93
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 85
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 79
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 79
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 77
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 67
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769 67
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 66
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 66
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 65
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 58
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692 57
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808 56