Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. 20711185

2010
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Therapeutic CTD_human Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys. 20494958

2010
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys. 20494958

2010
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Neuropeptide S reinstates cocaine-seeking behavior and increases locomotor activity through corticotropin-releasing factor receptor 1 in mice. 19339610

2009
Entrez Id: 1392
Gene Symbol: CRH
CRH
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Response to corticotropin-releasing hormone infusion in cocaine-dependent individuals. 19349312

2009
Entrez Id: 1392
Gene Symbol: CRH
CRH
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Evidence for beta1-adrenergic receptor involvement in amygdalar corticotropin-releasing factor gene expression: implications for cocaine withdrawal. 18596687

2009
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Therapeutic CTD_human Relapse to cocaine seeking increases activity-regulated gene expression differentially in the prefrontal cortex of abstinent rats. 18311559

2008
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Relapse to cocaine seeking increases activity-regulated gene expression differentially in the prefrontal cortex of abstinent rats. 18311559

2008
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Therapeutic CTD_human D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats. 18418874

2008
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats. 18418874

2008
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Therapeutic CTD_human Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration. 16541082

2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration. 16541082

2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Therapeutic CTD_human Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. 17332411

2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. 17332411

2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. 16971900

2006
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Therapeutic CTD_human Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. 16971900

2006
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Therapeutic CTD_human Cue-induced cocaine seeking and relapse are reduced by disruption of drug memory reconsolidation. 16738229

2006
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Cue-induced cocaine seeking and relapse are reduced by disruption of drug memory reconsolidation. 16738229

2006
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Therapeutic CTD_human Disrupting reconsolidation of drug memories reduces cocaine-seeking behavior. 16157275

2005
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Disrupting reconsolidation of drug memories reduces cocaine-seeking behavior. 16157275

2005
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Therapeutic CTD_human Cocaine dependence and d2 receptor availability in the functional subdivisions of the striatum: relationship with cocaine-seeking behavior. 15010698

2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Therapeutic CTD_human Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats. 15042275

2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats. 15042275

2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Biomarker CTD_human Cocaine dependence and d2 receptor availability in the functional subdivisions of the striatum: relationship with cocaine-seeking behavior. 15010698

2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.500 Therapeutic CTD_human Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists. 11923462

2002