| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
major histocompatibility complex, class I, B | 0.379 | 0.885 | 3.9E-05 |
|
disease | 0.700 | None | 0.939 | 4 | 0 | 1980 | 2019 | ||||||||
|
MEFV innate immuity regulator, pyrin | 0.440 | 0.885 | 1.0E-14 |
|
disease | 0.500 | None | 1.000 | 3 | 0 | 2000 | 2019 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.400 | None | 0.900 | 2 | 0 | 2008 | 2016 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.400 | None | 0.846 | 2 | 0 | 1996 | 2019 | ||||||||
|
intercellular adhesion molecule 1 | 0.364 | 0.962 | 3.5E-02 |
|
disease | 0.380 | None | 1.000 | 1 | 0 | 1996 | 2016 | ||||||||
|
TNF receptor superfamily member 1A | 0.409 | 0.923 | 0.99 |
|
disease | 0.150 | None | 1.000 | 1 | 0 | 2005 | 2019 | ||||||||
|
coagulation factor V | 0.441 | 0.846 | 5.9E-15 |
|
disease | 0.100 | None | 0.833 | 3 | 0 | 1996 | 2013 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.100 | None | 0.692 | 3 | 0 | 2002 | 2016 | ||||||||
|
interferon gamma | 0.288 | 0.962 | 0.47 |
|
disease | 0.100 | None | 1.000 | 2 | 0 | 2004 | 2019 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.100 | None | 0.909 | 2 | 0 | 2003 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 0.898 | 2 | 0 | 1992 | 2020 | ||||||||
|
coagulation factor II, thrombin | 0.415 | 0.885 | 1.1E-03 |
|
disease | 0.100 | None | 0.909 | 2 | 0 | 2000 | 2013 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
disease | 0.100 | None | 0.926 | 1 | 0 | 2008 | 2019 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
disease | 0.100 | None | 0.875 | 1 | 0 | 2003 | 2020 | ||||||||
|
interleukin 23 subunit alpha | 0.415 | 0.846 | 0.36 |
|
disease | 0.080 | None | 1.000 | 1 | 0 | 2008 | 2018 | ||||||||
|
C-C motif chemokine receptor 5 (gene/pseudogene) | 0.398 | 0.885 | 4.3E-10 |
|
disease | 0.080 | None | 1.000 | 1 | 0 | 2004 | 2016 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.070 | None | 0.714 | 1 | 0 | 2004 | 2019 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.070 | None | 1.000 | 1 | 0 | 1995 | 2020 | ||||||||
|
interleukin 4 | 0.332 | 0.962 | 4.7E-03 |
|
disease | 0.060 | None | 1.000 | 1 | 0 | 2003 | 2017 | ||||||||
|
interleukin 18 | 0.365 | 0.923 | 3.1E-02 |
|
disease | 0.060 | None | 0.833 | 1 | 0 | 2006 | 2018 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.060 | None | 1.000 | 1 | 0 | 2004 | 2013 | ||||||||
|
protein tyrosine phosphatase non-receptor type 22 | 0.438 | 0.846 | 3.5E-21 |
|
disease | 0.040 | None | 0.750 | 2 | 0 | 2007 | 2017 | ||||||||
|
mannose binding lectin 2 | 0.390 | 0.846 | 2.7E-03 |
|
disease | 0.040 | None | 1.000 | 1 | 0 | 2003 | 2017 | ||||||||
|
enolase 1 | 0.481 | 0.885 | 1.9E-05 |
|
disease | 0.040 | None | 1.000 | 1 | 0 | 2003 | 2019 | ||||||||
|
small ubiquitin like modifier 4 | 0.653 | 0.577 |
|
disease | 0.040 | None | 1.000 | 1 | 0 | 2008 | 2020 |