Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0001306
Disease: Acute alcoholic liver disease
Acute alcoholic liver disease
0.200 Therapeutic RGD Optimal ratio of 18α- and 18β-glycyrrhizic acid for preventing alcoholic hepatitis in rats. 31258651

2019

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0009766
Disease: Allergic Conjunctivitis
Allergic Conjunctivitis
0.200 Biomarker RGD Mast-cell activation augments the late phase reaction in experimental immune-mediated blepharoconjunctivitis. 12682842

2003

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
Anti-Basement Membrane Glomerulonephritis
0.200 Biomarker RGD Adenosine A2A receptor activation and macrophage-mediated experimental glomerulonephritis. 17898087

2008

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.290 Biomarker RGD Dietary fatty acid unsaturation levels, lipoprotein oxidation and circulating chemokine in experimentally induced atherosclerotic rats. 16259780

2005

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0004096
Disease: Asthma
Asthma
0.600 Biomarker RGD Role of the extracellular signal-regulated kinase 1/2 signaling pathway in regulating the secretion of bronchial smooth muscle cells in a rat model of chronic asthma. 18208670

2008

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0006272
Disease: Bronchiolitis Obliterans
Bronchiolitis Obliterans
0.200 Biomarker RGD Both MCP-1 and RANTES are functional in the formation of the fibroproliferative response that characterizes OB in this model, and their antagonization conferred protection against airway obstruction and epithelial loss. 14611812

2003

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0006272
Disease: Bronchiolitis Obliterans
Bronchiolitis Obliterans
0.200 Biomarker RGD A model of chronic lung allograft rejection in the rat. 19840961

2010

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest
0.210 Biomarker RGD Minocycline reduces neuronal death and attenuates microglial response after pediatric asphyxial cardiac arrest. 19756023

2010

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0600228
Disease: Cardiopulmonary Arrest
Cardiopulmonary Arrest
0.200 Biomarker RGD Minocycline reduces neuronal death and attenuates microglial response after pediatric asphyxial cardiac arrest. 19756023

2010

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
Chagas' disease without mention of organ involvement
0.200 Biomarker RGD Role of CCL3/MIP-1alpha and CCL5/RANTES during acute Trypanosoma cruzi infection in rats. 20452453

2010

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.220 Biomarker RGD Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats. 19535570

2009

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.280 Biomarker RGD Cytokine and chemokine expression in a rat endometriosis is similar to that in human endometriosis. 18595729

2008

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
0.200 Biomarker RGD Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat. 16215387

2005

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
Experimental Autoimmune Encephalomyelitis
0.200 Biomarker RGD The mRNA levels of CC chemokines, RANTES, MIP-1alpha and MCP-1, are inhibited in SIN-treated EAE rats. 17666800

2007

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 ModifyingMutation RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2
0.200 ModifyingMutation RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2
0.200 Therapeutic RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0015967
Disease: Fever
Fever
0.200 Biomarker RGD The present experiments show that hypothalamic CCR5 are functionally involved in the febrile response induced by RANTES, but not by MIP-1beta. 15066130

2004

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
0.220 Biomarker RGD Pretreatment with antibodies against RANTES/CCL5 prevented the hyperalgesic response, indicating that RANTES/CCL5 is able to interfere with the control of hyperalgesia at the level of the periaqueductal grey and suggesting that chemokine blockers could have analgesic properties. 18656466

2008

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
0.220 Biomarker RGD Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of peripheral nociceptors. 18076762

2007

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0020500
Disease: Hyperoxaluria
Hyperoxaluria
0.500 Biomarker RGD NF-kappaB and chemokine-cytokine expression in renal tubulointerstitium in experimental hyperoxaluria. Role of the renin-angiotensin system. 16284884

2005

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0020523
Disease: Immediate hypersensitivity
Immediate hypersensitivity
0.200 Biomarker RGD Quantitative expression levels of regulated on activation, normal T cell expressed and secreted and eotaxin transcripts in toluene diisocyanate-induced allergic rats. 15823807

2005

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0021368
Disease: Inflammation
Inflammation
0.220 Biomarker RGD In our study, we established the involvement of RANTES in an in vivo model of chronic inflammation induced by potassium permanganate, leading to calcified granulomas. 17164972

2007

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.220 Biomarker RGD DNA vaccination with naked DNA encoding MCP-1 and RANTES protects against renal injury in adriamycin nephropathy. 15882261

2005