×
Entrez Id: 18
Gene Symbol: ABAT
ABAT
Mental Depression
0.200
Biomarker
RGD
Enhanced GABAergic tone in the ventral pallidum: memory of unpleasant experiences?
21914462 2011
×
Entrez Id: 150
Gene Symbol: ADRA2A
ADRA2A
Mental Depression
0.530
Biomarker
RGD
Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective alpha2A-adrenoceptor antagonism.
20047711 2010
×
Entrez Id: 10476
Gene Symbol: ATP5PD
ATP5PD
Mental Depression
0.200
Therapeutic
RGD
Differential proteomic analysis of the anti-depressive effects of oleamide in a rat chronic mild stress model of depression.
25641667 2015
×
Entrez Id: 553
Gene Symbol: AVPR1B
AVPR1B
Mental Depression
0.210
Therapeutic
RGD
Vasopressin V1B receptor antagonists may be effective for the treatment of depression and anxiety and the objective of this study was to characterize the pharmacological profiles of two newly synthesized arginine vasopressin receptor 1B (V1B receptor) antagonists, TASP0233278 and TASP0390325.24654684 2014
×
Entrez Id: 581
Gene Symbol: BAX
BAX
Mental Depression
0.210
Therapeutic
RGD
Venlafaxine modulates depression-induced behaviour and the expression of Bax mRNA and Bcl-xl mRNA in both hippocampus and myocardium.
21308783 2011
×
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
Mental Depression
0.200
Therapeutic
RGD
Venlafaxine modulates depression-induced behaviour and the expression of Bax mRNA and Bcl-xl mRNA in both hippocampus and myocardium.
21308783 2011
×
Entrez Id: 627
Gene Symbol: BDNF
BDNF
Mental Depression
0.600
Biomarker
RGD
[Effects of chaihu shugan powder on the behavior and expressions of BDNF and TrkB in the hippocampus, amygdala, and the frontal lobe in rat model of depression ].
22097208 2011
×
Entrez Id: 627
Gene Symbol: BDNF
BDNF
Mental Depression
0.600
Therapeutic
RGD
Compared with the CUS+vehicle rats, the CUS+VPA rats showed a significant relief in depression -like behaviors and a decrease in the corticosterone level and corticotropin-releasing factor expression with increasing expression of BDNF .
24128869 2014
×
Entrez Id: 627
Gene Symbol: BDNF
BDNF
Mental Depression
0.600
Biomarker
RGD
Chronic antidepressant administration alleviates frontal and hippocampal BDNF deficits in CUMS rat.
20920483 2010
×
Entrez Id: 1020
Gene Symbol: CDK5
CDK5
Mental Depression
0.210
Therapeutic
RGD
Increased Cdk5/p35 activity in the dentate gyrus mediates depressive-like behaviour in rats.
21682945 2012
×
Entrez Id: 1129
Gene Symbol: CHRM2
CHRM2
Mental Depression
0.540
Biomarker
RGD
Expression profiling of a genetic animal model of depression reveals novel molecular pathways underlying depressive-like behaviours.
20830301 2010
×
Entrez Id: 1392
Gene Symbol: CRH
CRH
Mental Depression
0.600
Biomarker
RGD
Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders.
20860876 2011
×
Entrez Id: 1393
Gene Symbol: CRHBP
CRHBP
Mental Depression
0.520
Biomarker
RGD
Icariin attenuates chronic mild stress-induced dysregulation of the LHPA stress circuit in rats.
19631474 2010
×
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
Mental Depression
0.600
Biomarker
RGD
Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders.
20860876 2011
×
Entrez Id: 1395
Gene Symbol: CRHR2
CRHR2
Mental Depression
0.520
Biomarker
RGD
Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders.
20860876 2011
×
Entrez Id: 1544
Gene Symbol: CYP1A2
CYP1A2
Mental Depression
0.200
Biomarker
RGD
Hepatic drug metabolizing profile of Flinders Sensitive Line rat model of depression.
20595028 2010
×
Entrez Id: 1564
Gene Symbol: CYP2D7
CYP2D7
Mental Depression
0.210
Biomarker
RGD
Hepatic drug metabolizing profile of Flinders Sensitive Line rat model of depression.
20595028 2010
×
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
Mental Depression
0.210
Biomarker
RGD
Hepatic drug metabolizing profile of Flinders Sensitive Line rat model of depression.
20595028 2010
×
Entrez Id: 1621
Gene Symbol: DBH
DBH
Mental Depression
0.530
Biomarker
RGD
Degeneration of the locus ceruleus noradrenergic neurons in the stress-induced depression of rats.
19120095 2008
×
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
Mental Depression
0.530
Biomarker
RGD
Isolated Flinders Sensitive Line rats have decreased dopamine D2 receptor mRNA.
17558292 2007
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Mental Depression
0.600
Biomarker
RGD
Importantly, Par-4 and DRD2 mRNA levels significantly correlated with depression -like behaviors.
21596067 2011
×
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Mental Depression
0.250
Therapeutic
RGD
Estradiol decreases rat depressive behavior by estrogen receptor beta but not alpha: no correlation with plasma corticosterone.
24128867 2014
×
Entrez Id: 8772
Gene Symbol: FADD
FADD
Mental Depression
0.200
Therapeutic
RGD
Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal FADD.
30138765 2018
×
Entrez Id: 2623
Gene Symbol: GATA1
GATA1
Mental Depression
0.200
Biomarker
RGD
We also identify a transcriptional repressor, GATA1 , expression of which is higher in MDD and that, when expressed in PFC neurons, is sufficient to decrease the expression of synapse-related genes, cause loss of dendritic spines and dendrites, and produce depressive behavior in rat models of depression .
22885997 2012
×
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
Mental Depression
0.580
Therapeutic
RGD
Prenatal stress decreases glycogen synthase kinase-3 phosphorylation in the rat frontal cortex.
19815943 2010